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Gidijala, L. (author), Kiel, J.A.K.W. (author), Douma, R.D. (author), Seifar, R.M. (author), Van Gulik, W.M. (author), Bovenberg, R.A.L. (author), Veenhuis, M. (author), Van Klei, I.J. (author)
This study aimed at developing an alternative host for the production of penicillin (PEN). As yet, the industrial production of this β-lactam antibiotic is confined to the filamentous fungus Penicillium chrysogenum. As such, the yeast Hansenula polymorpha, a recognized producer of pharmaceuticals, represents an attractive alternative....
journal article 2009