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Miedema, S.A. (author)Sand, clay and rock have to be excavated for a variety of purposes, such as dredging, trenching, mining (including deep sea mining), drilling, tunnel boring and many other applications. Many excavations take place on dry land, but they are also frequently required in completely saturated conditions, and the methods necessary to accomplish them...book 2014
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Serracino Inglott, P. (author)Do the deviant acts carried out by the collective known as Anonymous qualify as vigilante activity, and if so, can they be justified? Addressing this question helps expose the difficulties of morally evaluating technologically enabled deviance. Anonymous is a complex, fluid actor but not as mysterious as popularly portrayed. Under a definition...journal article 2013
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Goossens, R.H.M. (author), Willemsen, H. (author)We read with interest the paper by Ferris and Shepley1 on a human-centered design project with university students on neonatal incubators. It is interesting to see that in the design solutions and concepts as presented by Ferris and Shepley,1 human-centered design played an important role. In 2005, a master thesis project was carried out in the...journal article 2013
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Pande, S. (author), Ertsen, M. (author), Sivapalan, M. (author)The ancient civilization in the Indus Valley civilization dispersed under extreme dry conditions; there are indications that the same holds for many other ancient societies. Even contemporary societies, such as the one in Murrumbidgee river basin in Australia, have started to witness a decline in overall population under increasing water...journal article 2013
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Otto, T. (author), Russchenberg, H.W.J. (author)In 2007, the horizontally scanning polarimetric X-band radar IDRA (IRCTR Drizzle Radar) was installed on top of the 213 m high mast at the Dutch meteorological observatory Cabauw Experimental Site for Atmospheric Research (CESAR) at Netherlands. This radar complements a large variety of measurement instruments at CESAR by providing information...journal article 2013
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Taskesen, E. (author), Hoogeboezem, R. (author), Delwel, R. (author), Reinders, M.J.T. (author)Probing protein-deoxyribonucleic acid (DNA) is gaining popularity as it sheds light on molecular mechanisms that regulate the expression of genes. Currently, tiling-arrays and next-generation sequencing technology can be used to measure these interactions. Both methods generate a signal over the genome in which contiguous regions of peaks on the...journal article 2013
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Righolt, C.H. (author), Slotman, J.A. (author), Young, I.T. (author), Mai, S. (author), Van Vliet, L.J. (author), Stallinga, S. (author)Various aspects of image filtering affect the final image quality in Structured Illumination Microscopy, in particular the regularization parameter and type of regularization function, the relative height of the side bands, and the shape of the apodization function. We propose an apodization filter without adjustable parameters based on the...journal article 2013
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Schepers, P. (author), Heinen, E. (author), Methorst, R. (author), Wegman, F.C.M. (author)Bicycle-motor vehicle crashes are concentrated along distributor roads where cyclists are exposed to greater volumes of high-speed motorists than they would experience on access roads. This study examined the road safety impact of network-level separation of vehicular and cycle traffic in Dutch urban networks, a strategy for which the term ...journal article 2013
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Van Wijk, A.J.M. (author)A sustainable world can only be achieved by an open collaboration between science, business and the public. That is why we create the Green Village: an innovative, lively, interactive and challenging environment where entrepreneurs, innovators, companies, artists, teachers and visitors can meet, work and play to develop, apply and experience...book 2013
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Meskers, A.J.H. (author), Voigt, D. (author), Spronck, J.W. (author)Many error sources can affect the accuracy of displacement measuring interferometer systems. In heterodyne interferometry two laser source frequencies constitute the finally detected wavefront. When the wavefronts of these source frequencies are non-ideal and one of them walks off the detector, the shape of the detected wavefront will vary. This...journal article 2013
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Van der Put, T.A.C.M. (author)A derivation is given of simplified, exact stability design rules according to limit analysis, applied to timber beam-columns. These rules are lacking but are necessary to be able to provide real and calculable reliability as is required according to European pacts and laws. Necessary therefore are the obtained exact combined bi-axial bending,...journal article 2013
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Van der Spek, J.E. (author), Bogaard, T.A. (author), Bakker, M. (author)Groundwater dynamics may play a significant role in landslides. A detailed model is developed of the groundwater dynamics in landslides in varved clays in the Trieves area in the French Alps. The varved clays consist of a sequence of alternating silt and clay layers, covered by a colluvium layer and intersected by fissures. The hydraulic...journal article 2013
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Pande, S. (author), Ertsen, M.W. (author)We propose and test the theory of endogenous change based on historical reconstructions of two ancient civilizations, Indus and Hohokam, in two water scarce basins, the Indus basin in the Indian subcontinent and the Lower Colorado basin in Southwestern United States. The endogenous institutional change sees changes in institutions as a sequence...journal article 2013
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Gonzalez-Ramos, D. (author), Van den Broek, M. (author), Van Maris, A.J.A. (author), Pronk, J.T. (author), Daran, J.M.G. (author)Background n-Butanol and isobutanol produced from biomass-derived sugars are promising renewable transport fuels and solvents. Saccharomyces cerevisiae has been engineered for butanol production, but its high butanol sensitivity poses an upper limit to product titers that can be reached by further pathway engineering. A better understanding of...journal article 2013
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Mugge, W. (author), Van der Helm, F.C.T. (author), Schouten, A.C. (author)Complex regional pain syndrome (CRPS) is characterized by pain and disturbed blood flow, temperature regulation and motor control. Approximately 25% of cases develop fixed dystonia. The origin of this movement disorder is poorly understood, although recent insights suggest involvement of disturbed force feedback. Assessment of sensorimotor...journal article 2013
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Haider, N. (author), Caratelli, D. (author), Yarovoy, A.G. (author)A comparative analysis of various reconfigurable andmultiband antenna concepts is presented. In order to satisfy the requirements for the advanced systems used in modern wireless and radar applications, different multiband and reconfigurable antennas have been proposed and investigated in the past years. In this paper, these design concepts have...journal article 2013
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Babaei, S. (author), Hulsman, M. (author), Reinders, M.J.T. (author), De Ridder, J. (author)Background Delineating the molecular drivers of cancer, i.e. determining cancer genes and the pathways which they deregulate, is an important challenge in cancer research. In this study, we aim to identify pathways of frequently mutated genes by exploiting their network neighborhood encoded in the protein-protein interaction network. To this end...journal article 2013
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Argiolu, R. (author), Van der Heijden, R. (author), Bos, I. (author), Marchau, V.A.W.J. (author)In recent years, a model was developed describing effects of Intelligent Transport Systems (ITS) on location preferences of office-keeping organisations in urbanised. The model is based on a Hierarchical Information Integration Approach, using Stated Preference data. The model indicates that ITS significantly contribute to office location...journal article 2013
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Van der Put, T.A.C.M. (author)The derivation is given of the combined bi-axial bending, compression and shear strength of timber beams. As for other materials the elastic–full plastic limit design approach applies, which is known to precisely explain and predict uniaxial bending strength behaviour. The derivation is based on choosing the location of the neutral line. This...journal article 2012
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Koopman, F.W. (author), Beekwilder, J. (author), Crimi, B. (author), Van Houwelingen, A. (author), Hall, R.D. (author), Bosch, D. (author), Van Maris, A.J.A. (author), Pronk, J.T. (author), Daran, J.M. (author)Background Flavonoids comprise a large family of secondary plant metabolic intermediates that exhibit a wide variety of antioxidant and human health-related properties. Plant production of flavonoids is limited by the low productivity and the complexity of the recovered flavonoids. Thus to overcome these limitations, metabolic engineering of...journal article 2012