Pages
- 1
- 2
- document
-
Kawasaki, S. (author)CMUTs (Capacitive Micromachined Ultrasonic Transducers) are causing a technological revolution. Research over the last decade showed that CMUTs can sufficiently replace traditional ultrasound technology based on the bulk PZT, along with other benefits such as lower assembly cost, broader bandwidth and monolithic integration capability with ASICs...doctoral thesis 2024
- document
-
Shiotani, T. (author), Ogura, N. (author), Okude, N. (author), Watabe, K. (author), Van Steen, C. (author), Tsangouri, E. (author), Lacidogna, G. (author), Czarnecki, S. (author), Chai, H. K. (author), Yang, Y. (author), Verstrynge, E. (author), Aggelis, D. G. (author)Aging infrastructure globally faces degradation, posing risks and requiring substantial repair investment. Strategic maintenance practices are crucial for evaluating structural conditions and ensuring sustainability. The growing demands on modern materials and structures necessitate enhanced health monitoring approaches. Shifting from...journal article 2024
- document
-
Guo, P. (author)This thesis presents the design and implementation of integrated ultrasound transceivers for use in transfontanelle ultrasonography (TFUS). Two generations of ultrasound transceiver ASICs integrated with PZT transducer arrays intended for TFUS are presented. In the first generation, a novel AFE design that combines an LNA with the continuous TGC...doctoral thesis 2023
- document
-
Hopf, Y.M. (author)This thesis describes the design of application-specific integrated circuits (ASICs) for high-frame-rate 3D intracardiac echocardiography (ICE) probes. The work follows the whole process from the analysis of the application to the testing of a prototype with all envisioned functionality. It starts with the evaluation of the main challenges posed...doctoral thesis 2023
- document
-
Li, H. (author), Li, X. (author), Collado Lara, G. (author), Lattwein, K.R. (author), Mastik, Frits (author), Beurskens, Robert (author), van der Steen, A.F.W. (author), Verweij, M.A. (author), de Jong, N. (author), Kooiman, Klazina (author)Ultrasound contrast-mediated medical imaging and therapy both rely on the dynamics of micron- and nanometer-sized ultrasound cavitation nuclei, such as phospholipid-coated microbubbles and phase-change droplets. Ultrasound cavitation nuclei respond non-linearly to ultrasound on a nanosecond time scale that necessitates the use of ultra-high...journal article 2023
- document
-
Saha, S. (author), Luckham, Paul F. (author), Garbin, V. (author)Hypothesis: High-frequency interfacial rheology of complex interfaces remains challenging yet it is central to the performance of multiphase soft matter products. We propose to use ultrasound-driven bubble dynamics to probe the high-frequency rheology of a colloid monolayer used as model system with controlled interactions and simultaneous...journal article 2023
- document
-
Luijten, Ben (author), Ossenkoppele, B.W. (author), de Jong, N. (author), Verweij, M.D. (author), Eldar, Yonina C. (author), Mischi, Massimo (author), van Sloun, Ruud J.G. (author)Ultrasound imaging is an attractive imaging modality due to its low-cost and real-time feedback, although it often falls short in image quality compared to MRI and CT imaging. Conventional ultrasound image reconstruction, such as Delay-and-Sum beamforming, is derived from maximum-likelihood estimation. As such, no prior information is exploited...conference paper 2023
- document
-
van Willigen, D.M. (author)This thesis describes the design, prototyping and evaluation of matrix-based clamp-on ultrasonic flow meters. Several new measurement techniques are presented as well as an Application-Specific Integrated Circuit (ASIC) designed for accurate measurement of flow velocity with matrix transducers.<br/><br/>The influence of circuit topologies on the...doctoral thesis 2022
- document
-
Veerkamp, Kirsten (author), van der Krogt, Marjolein M. (author), Harlaar, J. (author), O’Brien, Thomas D. (author), Kalkman, Barbara (author), Seth, A. (author), Bar-On, Lynn (author)Neuromusculoskeletal models can be used to evaluate aberrant muscle function in cerebral palsy (CP), for example by estimating muscle and joint contact forces during gait. However, to be accurate, models should include representative musculotendon parameters. We aimed to estimate personalised parameters that capture the mechanical behaviour...journal article 2022
- document
-
Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnelsBeekers, Inés (author), Langeveld, Simone A.G. (author), Meijlink, Bram (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing the cell membrane permeability. To aid development of a safe and effective therapeutic microbubble, more insight into the microbubble-cell interaction is needed. In this in vitro study we aimed to investigate the initial 3D morphology of the endothelial...journal article 2022
- document
-
Polat, S. (author), Kortlever, R. (author), Eral, H.B. (author)The selective separation of ions is a major technological challenge having far-ranging impacts from product separation in electrochemical production of base chemicals from CO<sub>2</sub> to water purification. In recent years, ion-selective electrochemical systems leveraging redox-materials emerged as an attractive platform based on their...journal article 2022
- document
-
Massaad Mouawad, J.M. (author)Ultrasonic flow meters are widely applied to measure flow in a variety of applications. The vast majority of ultrasonic flow meters are based on the measurement of the transit time of an acoustic pulse through the fluid. This can either be done in-line, by inserting a spool piece with ultrasonic transducers into the pipe carrying the fluid, or...doctoral thesis 2021
- document
-
Collado Lara, G. (author), Heymans, Sophie V. (author), Rovituso, M. (author), Carlier, Bram (author), Toumia, Yosra (author), Verweij, M.D. (author), Vos, H.J. (author), de Jong, N. (author), Daeichin, V. (author)The potential of proton therapy to improve the conformity of the delivered dose to the tumor volume is currently limited by range uncertainties. Injectable superheated nanodroplets have recently been proposed for ultrasound-based in vivo range verification, as these vaporize into echogenic microbubbles on proton irradiation. In previous...journal article 2021
- document
-
Kouijzer, Joop J.P. (author), Lattwein, Kirby R. (author), Beekers, Inés (author), Langeveld, Simone A.G. (author), Leon-Grooters, Mariël (author), Strub, Jean Marc (author), Oliva, Estefania (author), de Jong, N. (author), van der Steen, A.F.W. (author)Bacterial biofilms are a huge burden on our healthcare systems worldwide. The lack of specificity in diagnostic and treatment possibilities result in difficult-to-treat and persistent infections. The aim of this in vitro study was to investigate if microbubbles targeted specifically to bacteria in biofilms could be used both for diagnosis as...journal article 2021
- document
-
Beekers, D.I. (author), Vegter, Merel (author), Lattwein, Kirby R. (author), Mastik, Frits (author), Beurskens, Robert (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)Ultrasound insonification of microbubbles can locally increase vascular permeability to enhance drug delivery. To control and optimize the therapeutic potential, we need to better understand the underlying biological mechanisms of the drug delivery pathways. The aim of this in vitro study was to elucidate the microbubble-endothelial cell...journal article 2020
- document
-
Ouyang, B. (author), Li, Yanlu (author), Kruidhof, Marten (author), Horsten, R.C. (author), Baets, Roel (author), van Dongen, K.W.A. (author), Caro-Schuurman, J. (author)We report a highly sensitive ultrasound sensor based on an integrated photonics silicon Mach-Zehnder interferometer (MZI). One arm of the MZI is located on a thin membrane, acting as the sensing part of the device. Ultrasound waves excite the membrane's vibrational mode, thus inducing modulation of the MZI transmission. The measured sensor...conference paper 2020
- document
-
Kooiman, Klazina (author), Roovers, Silke (author), Langeveld, Simone A.G. (author), Kleven, Robert T. (author), Dewitte, Heleen (author), O'Reilly, Meaghan A. (author), Escoffre, Jean Michel (author), Bouakaz, Ayache (author), Verweij, M.D. (author)Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for beneficial tissue bio-effects are actively under development. The mechanical oscillations of circulating microbubbles, the most widely investigated cavitation nuclei, which may also encapsulate or shield a therapeutic agent in the bloodstream,...review 2020
- document
-
Beekers, D.I. (author), Mastik, Frits (author), Beurskens, Robert (author), Tang, Phoei Ying (author), Vegter, Merel (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)Ultrasound insonification of microbubbles can locally enhance drug delivery, but the microbubble–cell interaction remains poorly understood. Because intracellular calcium (Ca<sub>i</sub> <sup>2+</sup>) is a key cellular regulator, unraveling the Ca<sub>i</sub> <sup>2+</sup> fluctuations caused by an oscillating microbubble provides crucial...journal article 2020
- document
-
Saint-Michel, B.F.B. (author), Garbin, V. (author)Bubbles in complex fluids are often desirable, and sometimes simply inevitable, in the processing of formulated products. Bubbles can rise by buoyancy, grow or dissolve by mass transfer, and readily respond to changes in pressure, thereby applying a deformation to the surrounding complex fluid. The deformation field around a stationary,...review 2020
- document
-
Haus, Michael (author), Ding, Aaron Yi (author), Wang, Qing (author), Toivonen, Juhani (author), Tonetto, Leonardo (author), Tarkoma, Sasu (author), Ott, Jorg (author)The number of deployed Internet of Things (IoT) devices is steadily increasing to manage and interact with community assets of smart cities, such as transportation systems and power plants. This may lead to degraded network performance due to the growing amount of network traffic and connections generated by various IoT devices. To tackle...conference paper 2019
Pages
- 1
- 2