A multi-axis robot-based bioprinting system supporting natural cell function preservation and cardiac tissue fabrication

Despite the recent advances in artificial tissue and organ engineering, how to generate large size viable and functional complex organs still remains as a grand challenge for regenerative medicine. Three-dimensional bioprinting has demonstrated its advantages as one of the major methods in fabricating simple tissues, yet it still faces...

Determining finite-width-correction factors for fatigue crack growth prediction in GLARE using the equivalent compliance method

Finite-width-correction factors (FWCF) are required for GLARE to accurately predict fatigue crack growth using linear elastic fracture mechanics. As demonstrated in earlier work, these factors effectively correct for the change in specimen compliance, which in GLARE relates to intact fibre layers and the formation of delaminations between...

On the physics of applying finite width and geometry correction factors in fatigue crack growth predictions of GLARE

In general, a finite width correction to stress intensity factor (SIF) is required in the fatigue crack growth. The finite width correction factor can be explained physically from the energy point of view. It is assumed that the finite width correction factor primarily constitutes an energy correction factor, i.e. it corrects the applied load...