Substrate-Specific Evolution of Amine Dehydrogenases for Accessing Structurally Diverse Enantiopure (R)-β-Amino Alcohols

The biocatalytic oxidative deamination of β-amino alcohols holds significant practical potential in kinetic resolution and/or deracemization process to access (R)-β-amino alcohols. This study exemplifies a notable instance of acquisition and utilization of this valuable oxidative deamination activity. Initially, the mutation N261M (M0) was...

A Thermoelectric Energy Harvesting System Assisted by A Piezoelectric Transducer Achieving 10-mV Cold-Startup and 82.7% Peak Efficiency

This article presents a 10mV-startup-voltage thermoelectric energy harvesting system, assisted by a piezoelectric generator (PEG) as a cold starter. It exploits the fact that when a thermoelectric energy harvesting system is implemented in a place where kinetic energy is also present, the PEG starter can provide a clock signal to start the...

DeepPick: A Deep Learning Approach to Unveil Outstanding Users Ranking with Public Attainable Features

Outstanding users (OUs) denote the influential, 'core' or 'bridge' users in online social networks. How to accurately detect and rank them is an important problem for third-party online service providers and researchers. Conventional efforts, ranging from early graph-based algorithms to recent machine learning-based approaches, typically rely on...

Continual driver behaviour learning for connected vehicles and intelligent transportation systems: Framework, survey and challenges

Modelling, predicting and analysing driver behaviours are essential to advanced driver assistance systems (ADAS) and the comprehensive understanding of complex driving scenarios. Recently, with the development of deep learning (DL), numerous driver behaviour learning (DBL) methods have been proposed and applied in connected vehicles (CV) and...

A Fractional-N Digitally Intensive PLL Achieving 428-fs Jitter and <-54-dBc Spurs Under 50-mV _ppSupply Ripple

In this article, we present a 4.5-5.1-GHz fractional-N digitally intensive phase-locked loop (DPLL) capable of maintaining its performance in face of a large supply ripple, thus enabling a direct connection to a switched-mode dc-dc converter. Supply pushing of its inductor-capacitor (LC) oscillator is suppressed by properly replicating the...

A Cryo-CMOS Oscillator With an Automatic Common-Mode Resonance Calibration for Quantum Computing Applications

This article presents a 4-to-5GHz LC oscillator operating at 4.2K for quantum computing applications. The phase noise (PN) specification of the oscillator is derived based on the control fidelity for a single-qubit operation. To reveal the substantial gap between the theoretical predictions and measurement results at cryogenic temperatures, a...

基于强化学习补偿的地面无人战车行进间跟瞄自适应控制

To deal with the nonlinear interference caused by chassis movement and road surface undulations with the tracking and aiming of unmanned combat ground vehicles, a tracking and aiming adaptive control method for unmanned combat ground vehicles on the move based on reinforcement learning compensation is proposed. This method consists of a main...

A 2.6-to-4.1GHz Fractional-N Digital PLL Based on a Time-Mode Arithmetic Unit Achieving -249.4dB FoM and -59dBc Fractional Spurs

In a fractional-N PLL, it is beneficial to minimize the input range of its phase detector (PD) as it promotes better linearity and higher PD gain for suppressing noise contributions of the following loop components. This can be done by canceling the predicted instantaneous time offset between the frequency reference (FREF) and the variable...

Ecological impact of land reclamation on Jiangsu coast (China): A novel ecotope assessment for Tongzhou Bay

China's continuous and rapid economic growth has led to the reclamation of large sections of the intertidal mud coast in combination with port construction, such as that of the proposed Tongzhou Bay port on the Jiangsu coast. These reclamations threaten the local ecosystem services. An ecotope distribution map was created and a hydrodynamic...

Understanding the Working Time of Developers in IT Companies in China and the United States

We identified three temporal patterns shown in commit activities among Chinese and American companies and found that Chinese businesses are more likely to follow long work hours than American ones. We also conducted a survey on the trends of, reasons for, and results of overtime work. Our study could provide references for developers to...

A 200dB FoM 4-to-5GHz Cryogenic Oscillator with an Automatic Common-Mode Resonance Calibration for Quantum Computing Applications

Low-power, low phase noise (PN) cryogenic frequency generation is required for the control electronics of quantum computers. To avoid limiting the performance of quantum bits, the frequency noise of a PLL should be &lt; 1.9 kHz rms [1]. However, it is challenging for RF oscillators, as the heart of frequency synthesizers to satisfy such a...

Building for nature: Preserving threatened bird habitat in port design

The fast economic development of the People's Republic of China has created an increasing demand for usable land, resulting in large-scale land reclamations along the coastal zone. One of these regions is Tongzhou Bay (Jiangsu coast), a region characterized by large intertidal mudflats and deep tidal channels with potential for the...