Searched for: contributor%3A%22Ghatkesar%2C+M.K.+%28graduation+committee%29%22
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Kunkels, Lorenzo (author)
Patients with orthopaedic implants often experience implant-associated infections (IAI), one of the most prominent causes for implant failure. IAIs are caused by pathogens adhering to the implant surface. One method to prevent IAIs is through the use of surface topography modifications. Cellular behaviour has been shown to be influenced by...
master thesis 2019
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Onderdelinden, Suzanne (author)
In the last few years organ-on-chip (OoC) has been emerging as a new method for more reliable research to screen the effects of new drugs on the body. This is a novel technology mimicking the in vivo environment of tissue cells, making it a more suitable candidate for experimentation than traditional 2D cell cultures. However, in order to ensure...
master thesis 2020
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Kramer, Henrie (author)
Microvalves are useful components for several microfluidic applications in which they control the fluid flow in a microfluidic system. Most microvalves to date are made by using silicon micro-machining, which is a complex manufacturing process, or soft lithography using Polydimethylsiloxane (PDMS) which has a high gas permeability. Next to that...
master thesis 2022
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Mollaie Daryani, Mehdi (author)
In connection with growing in applications of nanoparticles in various industrial sectors such as cosmetics and pharmaceuticals, the demand for in-line identification and characterization of nanoparticles suspended in fluids has increased. In addition to that, nanoparticles in general and nanoplastics in particular, can easily contaminate air...
master thesis 2021
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Janssen, Janeau (author)
In-situ sample holders with double-tilting capabilities are used to insert and position samples inside a transmission electron microscope for dynamic imaging. However, the performance of these sample holders, regarding energy-dispersive X-ray spectroscopy (EDS) analysis, is not on par with their single-tilt counterparts. By analyzing the EDS...
master thesis 2018
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Roos, Brian (author)
Microglia, the resident macrophages of the central nervous system, are key players in neuroinflammation and neurodegenerative diseases, such as Alzheimer’s and Parkinson’s. These cells represent promising cellular targets for therapeutic intervention, therefore a detailed cellular biological knowledge of microglia is of paramount importance....
master thesis 2021
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Bälz, Koona-Garth Keith (author)
Inkjet printing offers an additive manufacturing method for the production of thin films. A variety of inkjet printed materials can be printed, including conductive and electroactive materials. Existing inkjet printed ferroelectric polymer actuators all utilize silver conductive layers and P(VDF-TrFE) for the electroactive layer. This thesis...
master thesis 2019
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Keşkekler, Ata (author)
From the earliest days, the phenomenon of levitation has always aroused the curiosity of humankind due to its mysterious and unique nature. Levitation systems are particularly interesting because of their non-contact characteristic which provides the possibility to isolate the levitated object from environmental effects like mechanical friction...
master thesis 2018
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Shojaei Baghini, Mahdieh (author)
Cardiac cells derived from stem cells exhibit cellular contractions when cultured in vitro. They can be integrated with polymeric platforms consisting of micropillars, which act as anchors and pre-load for engineered heart tissue (EHT). The biomechanical response is often characterized using optical microscopy to track the displacement of pillar...
master thesis 2020
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Hu, Haotian (author)
Photonics biosensors convert biomolecular interactions into quantifiable optical signals for biomedical analysis, which enable continuous monitoring of health indicators. Among them the microring resonator has a good sensing performance and a very broad application prospect. This thesis studies sensing with microfluidic integrated microring...
master thesis 2023
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Swuste, Rolf (author)
The Atomic Force Microscope (afm) is a small scale measuring device, with a lot of benefits over other existing measuring techniques. Unfortunately, measurement speed is not one of them. Many have tried and succeeded to improve the measurement speed, but there is still room for improvement.<br/>By passively lowering the Q-factor, a measurement...
master thesis 2017
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Zhang, Chuqian (author)
Cell behavior in vitro can be regulated by mechanical stimulation. Cytostretch is an Organ-on-Chip (OOC) platform that allows cyclic stretching tissue in culture. Its pneumatic actuation can hinder it from microfluidic systems integration. A dielectric elastomer actuator (DEA) was developed and fabricated in this thesis for Cytostretch as an...
master thesis 2019
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de Winter, Jikke (author)
Biosensing properties like mass, density and stiffness on a single cell level can help diagnose diseases. Mass sensing of cells and subcellular components is typically performed with resonant microstructures. Recently such microstructures were fabricated using an emerging 3D printing technique called two-photon polymerization (2PP) contrary to...
master thesis 2022
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Vis, Bas (author)
Atherosclerotic plaque rupture is the main cause of acute myocardial infarction and stroke, the two leading causes of death worldwide. Rupture of plaque tissue is a mechanical event, where plaque stress or strain locally exceeds its strength. Biomechanical studies agree with histopathological findings that a large lipid pool and thin fibrous cap...
master thesis 2019
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Singh, Sampuran (author)
Small satellites require efficient propulsion systems for attitude and orbit control. This thesis focuses on the development and characterization of two distinct types of micro-resistojet thrusters, namely Vaporizing Liquid Micro-resistojet (VLM) and Low Pressure Micro-resistojet (LPM). Both concepts are developed at TU Delft and are designed to...
master thesis 2023
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Silvestrini, Stefano (author)
The growing needs of nano- and pico-satellite missions require several enhancements in micro-propulsion capabilities to enable the satellites to perform an increasing variety of orbital maneuvers. Among them, the possibility to accurately control the thrust would open up new scenarios for nano- and pico-satellites applicability to include, for...
master thesis 2017
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Shan, Jichao (author)
Proteins play a key role in many biological processes and are thus useful indicators of health and disease states. Since the size of proteins is few hundred nanometers, it is necessary to explore new techniques to manipulate and 'read' them. This thesis aims to identify and build a platform that enables sub-micron bead manipulation, which will...
master thesis 2022
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Kothari, Nimit (author)
In the past few decades, there has been a growing demand for low-cost disposable sensors to be utilized in hazardous and toxic environments such as high temperature and chemically aggressive environments, which can lead to irreversible damage to the sensor. Moreover, by cost reduction, they become more attractive for utilization in developing...
master thesis 2019
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Zafeiropoulou, Katerina (author)
Degenerative disc disease (DDD) is the accelerated process of intervertebral disc decay (decrease of disc thickness, enhanced cell death, ECM damage and collagen loss etc.), accompanied with pain, as well as structural and functional failure. So far, there are no therapies that can inhibit or even reverse the degenerative progress of this...
master thesis 2017
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Struijk, Victor (author)
Life at low-Reynolds numbers regime is intriguing. Single motile bacteria are known to exhibit erratic behaviour; they swim in what is known as a random walk, alternating between periods of swimming straight and abrupt moments of re-orientation. Yet in dense populations, cells of E.coli have been reported to exhibit weak synchronization and self...
master thesis 2023
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