Geobacter sulfurreducens microcolony growth and its single bionanowire conductivity: On potential and growth

The long-range electron transport of exoelectrogenic bacterium G. sulfurreducens<br/>was recently discovered to be facilitated by a network of conductive protein wires. In<br/>chapter 1 we provide an overview of our current understanding of these protein wires.<br/>This newly discovered feature of the model organism for microbial fuel cells may...

The path towards prediction: An exploration of the evolutionary dynamics of the yeast polarity network

All living systems possess the ability to evolve. This ability has allowed life to adopt a large diversity of shapes, colors, sizes and lifestyles. However, despite being a fundamental property of life, our knowledge of what makes living systems evolvable is limited. The fact that evolution can be sometimes be hopelessly unpredictable while in...

Complex Simplicity: Towards reconstituting Cdc42-based polarity establishment

Saccharomyces cerevisiae proliferates through budding, where a daughter cell grows by budding off one side of the mother. The first step towards budding is polarity establishment: here Cdc42 accumulates in one spot on the membrane, marking the site of bud-emergence. Cdc42 accumulation arises through at least two interconnected regulatory...