Towards Direct Co-culture Models for Osteoimmunodulatory Studies: An exploratory study on the effects of nanopatterns and shear stress on cellular crosstalk

In the last two decades, it has been generally accepted that the interaction between bone and immune cells is critical in the process of bone healing and regeneration. Steering this immune response with the development of biomaterials could lead to implant acceptance in the long term. The understanding of osteoimmunological responses is of high...

A systematic study of macrophages’ response to submicron pillars

Objective: Advances in the field of biomaterials have positively affected implant acceptance and nowadays nanostructured surfaces are known to have a positive effect on bone regeneration. The development of the field of osteoimmunology has contributed to a steadily increasing interest towards the investigation of the immunomodulatory effect of...