Searched for: contributor%3A%22Van+Vliet%2C+L.J.+%28promotor%29%22
(1 - 20 of 55)
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Loozen, G.B. (author)Optofluidic lab-on-a-chips (LOCs) employing a dual-waveguide trap for optical trapping and Raman spectroscopy have proven to be attractive and potent tools for high throughput chemical fingerprinting of bio-particles for disease diagnosis. Among the relevant bio-particles are extracellular vesicles (EVs) which a been proven through recent...doctoral thesis 2023
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Vigueras Guillén, J.P. (author)The corneal endothelium, a non-regenerative layer of cells controlling the state of corneal hydration, is the most critical tissue of the cornea. Quantifying its health status is not only important to diagnose and treat certain corneal diseases but also relevant to the execution and evaluation of many eye surgeries. By means of specular...doctoral thesis 2022
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Ghafaryasl, B. (author)Early diagnosis of retinal diseases such as glaucoma will benefit from unbiased an precise estimation of both optical and structural properties of the RNFL as they provide a better understanding of the tissue characteristics. The main objective of this thesis was first to improve the estimation of the attenuation coefficients of layered samples...doctoral thesis 2021
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van Valenberg, W. (author)Magnetic resonance imaging (MRI) is the primary modality for the imaging of soft tissues (e.g. brain, muscle, liver). Therefore, it is an essential radiological tool for diagnosis and surgical planning. The contrast in MR images is due to tissues responding differently to the magnetic fields generated by the scan-ning system. This response can...doctoral thesis 2020
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van der Graaff, L. (author)This thesis explores a novel optical architecture for Whole Slide Imaging (WSI). This new architecture allows for multi-focal (3D) image acquisitions in a single scan pass. The multi-focal imaging capability is used to demonstrate 3D phase imaging and 3D imaging of thick tissue sections on a prototype scanner. Further, instrumentation for the...doctoral thesis 2020
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Ouyang, B. (author)Ultrasound sensors based on integrated photonics devices provide a new solution to meet the miniaturization demand for the detection functionality of transducers. An important example is the silicon ring-resonator (RR) ultrasound sensor developed in our department. This sensor combines a small footprint with high sensitivity and a low detection...doctoral thesis 2020
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Heldens, J.T. (author)An important aspect in increasing our health and safety is the development of new sensors for screening drinking water samples for the presence of microbiological contaminants.The main problem associated with the detection and identification of these microbial contaminants is the long process time. The majority of the time is required fortheir...doctoral thesis 2019
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Zhang, T. (author)Patients with colorectal cancer are frequently presented with liver metastases for which (partial) resection is often the best therapy. However, the future remnant liver, the remaining part of the liver after resection, should allow adequate liver function to avoid liver failure. This thesis presents novel methods for the accurate voxel-wise...doctoral thesis 2019
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Adal, K.M. (author)Diabetic retinopathy (DR) is a complications of diabetes mellitus, which progressively damages small retinal blood vessels and result in vision loss if not treated and controlled timely. Because of an increase in the risk of vision loss with the duration of diabetes and the latency between DR progression and early symptoms, diabetic patients...doctoral thesis 2019
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Filatova, O.G. (author)Human brain consists of grey and white matter. Grey matter largely forms the<br/>outer layer of the brain, and is responsible for decision making and functioning<br/>of the human body. Complementary, the white matter (WM) contains the<br/>communication pathways between the grey matter areas. Diffusion-weighted<br/>magnetic resonance imaging ...doctoral thesis 2019
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Trull, A.K. (author)Disease model systems, such as the zebrafish, play an important role in understanding the onset of diseases like cancer and monitor the efficacy of new drugs. In the past, non-invasive methods for screening, diagnostics and treatment monitoring were intrinsically from the outside. In the past decades, there has been a strong drive to look inside...doctoral thesis 2018
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van der Horst, J. (author)Optical imaging is one of the primary tools in biological and medical research. Over the years many different optical imaging modalities have been developed that have driven the imaging performance in terms of image resolution, contrast, imaging time, and maximum allowed sample size. The goal of this work is to develop techniques for 3D optical...doctoral thesis 2018
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Arkesteijn, G.A.M. (author)The brain’s white matter mainly consists of (myelinated) axons that connect different parts of the brain. Diffusion-weighted MRI (DW-MRI) is a technique that is particularly suited to image this white matter. The MRI signal in DW-MRI is sensitized to diffusion of water in the microstructure by introducing strong bipolar gradients in the MRI...doctoral thesis 2018
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Alshuhail, A.A. (author)One of the most crucial estimates obtained from reflection seismology is the seismic image. It provides a map of the subsurface reflectivities. However, in order to construct an accurate map an accurate propagation velocity model is needed. For simple geologic environments an isotropic velocity model is sufficient, however, for complex geologic...doctoral thesis 2017
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- Novosel, J. (author) doctoral thesis 2017
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Shakeri, S.M. (author)Digital pathology is based on the use of digital images of tissues for diagnosis of diseases. In the emerging clinical practice of digital pathology, images of tissue slides are acquired with a high-resolution and high-throughput automated microscope, a so called Whole Slide Imaging (WSI) system. We designed, built and characterized a modular...doctoral thesis 2017
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- Chakrova, N. (author) doctoral thesis 2017
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van Schie, J.J.N. (author)Dynamic Contrast Enhanced MRI is an important technique to assess the pharmacokinetic properties of tissues. This thesis addresses two major steps necessary for quantitative DCE-MRI: the estimation of the tissue’s T1-time and local B1-field strength, and the estimation of the time-dependent concentration of contrast agent in the blood supply to...doctoral thesis 2016
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Davydenko, M.V. (author)Seismic imaging aims at revealing the structural information of the subsurface using the reflected wavefields captured by sensors usually located at the surface. Wave propagation is a complex phenomenon and the measured data contain a set of backscattered events including not only primary reflections, but also surface-related and interbed...doctoral thesis 2016
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- Naziroglu, R.E. (author) doctoral thesis 2016
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