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Spectroscopic optical coherence tomography at 1200 nm for lipid detection

Kuttippurath, Vivek (author), Slijkhuis, Nuria (author), Liu, Shengnan (author), van Soest, G. (author)

Significance: Spectroscopic analysis of optical coherence tomography (OCT) data can yield added information about the sample's chemical composition, along with high-resolution images. Typical commercial OCT systems operate at wavelengths that may not be optimal for identifying lipid-containing samples based on absorption features. Aim: The...

journal article 2023

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Ankle-Foot-Orthosis “Hermes” Compensates Pathological Ankle Stiffness of Chronic Stroke—A Proof of Concept

Rodriguez Hernandez, K.E. (author), de Groot, J.H. (author), Baas, Frank (author), Stijntjes, M. (author), Grootendorst, E.R.M. (author), Schiemanck, S.K. (author), van der Helm, F.C.T. (author), van der Kooij, H. (author), Mugge, W. (author)

Individuals with an upper motor neuron syndrome, e.g., stroke survivors, may have a pathological increase of passive ankle stiffness due to spasticity, that impairs ankle function and activities such as walking. To improve mobility, walking aids such as ankle-foot orthoses and orthopaedic shoes are prescribed. However, these walking aids...

journal article 2023

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Mild Stroke, Serious Problems: Limitations in Balance and Gait Capacity and the Impact on Fall Rate, and Physical Activity

Roelofs, Jolanda M.B. (author), Zandvliet, Sarah B. (author), Schut, I.M. (author), Huisinga, Anouk C.M. (author), Schouten, A.C. (author), Hendricks, Henk T. (author), de Kam, Digna (author), Aerden, Leo A.M. (author), Bussmann, J.B.J. (author), Geurts, Alexander C.H. (author), Weerdesteyn, Vivian (author)

Background: After mild stroke persistent balance limitations may occur, creating a risk factor for fear of falling, falls, and reduced activity levels. Objective. To investigate whether individuals in the chronic phase after mild stroke show balance and gait limitations, elevated fall risk, reduced balance confidence, and physical activity...

journal article 2023

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Magnitude and variability of individual elbow load in repetitive baseball pitching

van Trigt, B. (author), van Hogerwou, Thomas (author), Leenen, A.J.R. (author), Hoozemans, Marco J.M. (author), van der Helm, F.C.T. (author), Veeger, H.E.J. (author)

In baseball pitchers the elbow is exposed to high and repetitive loads (i.e. external valgus torque), caused by pitching a high number of balls in a practice session or game. This can result in overuse injuries like the ulnar collateral ligament (UCL) injury. To understand injury mechanisms, the effect of repetitive pitching on the elbow load...

journal article 2023

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The relevance of reducing Veress needle overshooting

Horeman, T. (author), Postema, R.R. (author), Fischer, T. (author), Calleja-Agius, J. (author), Camenzuli, C. (author), Alvino, L. (author), Hardon, S.F. (author), Bonjer, H. J. (author)

Safe insertion of the Veress needle during laparoscopy relies on the surgeons’ technical skills in order to stop needle insertion just in time to prevent overshooting in the underlying organs. To reduce this risk, a wide variety of Veress needle systems were developed with safety mechanisms that limit the insertion speed, insertion depth or...

journal article 2023

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Developing a Digital Medication Adherence Intervention for and With Patients With Asthma and Low Health Literacy: Protocol for a Participatory Design Approach

Faber, J.S. (author), Poot, Charlotte C. (author), Dekkers, Tessa (author), Romero Herrera, N.A. (author), Chavannes, N.H. (author), Meijer, Eline (author), Visch, V.T. (author)

Background: Current eHealth interventions are poorly adopted by people with low health literacy (LHL) as they often fail to meet their needs, skills, and preferences. A major reason for this poor adoption is the generic, one-size-fits-all approach taken by designers of these interventions, without addressing the needs, skills, and preferences...

journal article 2023

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Examining the role of intrinsic and reflexive contributions to ankle joint hyper-resistance treated with botulinum toxin-A

van’t Veld, Ronald C. (author), Flux, Eline (author), van Oorschot, Wieneke (author), Schouten, A.C. (author), van der Krogt, Marjolein M. (author), van der Kooij, H. (author), Vos-van der Hulst, Marije (author), Keijsers, Noël L.W. (author), van Asseldonk, Edwin H.F. (author)

Background: Spasticity, i.e. stretch hyperreflexia, increases joint resistance similar to symptoms like hypertonia and contractures. Botulinum neurotoxin-A (BoNT-A) injections are a widely used intervention to reduce spasticity. BoNT-A effects on spasticity are poorly understood, because clinical measures, e.g. modified Ashworth scale (MAS),...

journal article 2023

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EASIER: A new model for online learning of minimally invasive surgery skills

Oropesa, Ignacio (author), Sánchez-Peralta, Luisa F. (author), Chmarra, M.K. (author), Berner-Juhos, Krisztina (author), Tiu, Calin (author), Mettouris, Christos (author), Blas Pagador, José (author), Post, Joeri (author), Dankelman, J. (author)

Introduction: Technology Enhanced Learning (TEL) can provide the tools to safely master minimally invasive surgery (MIS) skills in patient-free environments and receive immediate objective feedback without the constant presence of an instructor. However, TEL-based systems tend to work isolated from one another, focus on different skills, and...

journal article 2023

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Identifying lipid traces of atherogenic mechanisms in human carotid plaque

Slijkhuis, Nuria (author), Mirzaian, Mina (author), Korteland, Suze Anne (author), Heijs, Bram (author), van Gaalen, Kim (author), Nieuwenhuizen, Ingeborg (author), van der Heiden, Kim (author), Claude, Emmanuelle (author), van Soest, G. (author)

Background and aims: Lipids play an important role in atherosclerotic plaque development and are interesting candidate predictive biomarkers. However, the link between circulating lipids, accumulating lipids in the vessel wall, and plaque destabilization processes in humans remains largely unknown. This study aims to provide new insights into...

journal article 2023

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Quantifying Within-Individual Elbow Load Variability in Youth Elite Baseball Pitchers and Its Role in Overuse Injuries

van Trigt, B. (author), Bouman, F.F. (author), Leenen, Antonius J. R. (author), Hoozemans, Marco J.M. (author), van der Helm, F.C.T. (author), Veeger, H.E.J. (author)

Medial elbow overuse injuries are rising in baseball. The external valgus torque magnitude is a possible risk factor for medial elbow injuries. The magnitude on its own cannot explain why one pitcher sustains an injury and another does not. Therefore, the aim of this study is to describe the within-individual external valgus torque variability...

journal article 2022

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Unperceived motor actions of the balance system interfere with the causal attribution of self-motion

Tisserand, Romain (author), Rasman, Brandon G. (author), Omerovic, Nina (author), Peters, Ryan M. (author), Forbes, P.A. (author), Blouin, Jean Sébastien (author)

The instability of human bipedalism demands that the brain accurately senses balancing self-motion and determines whether movements originate from self-generated actions or external disturbances. Here, we challenge the longstanding notion that this process relies on a single representation of the body and world to accurately perceive postural...

journal article 2022

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Fastball pitching performance only slightly decreases after mobility impediment of the pelvis and trunk—Do (catch-up) compensation strategies come into play?

Leenen, A.J.R. (author), van Trigt, B. (author), Hoozemans, M. J.M. (author), Veeger, H.E.J. (author)

Background: Baseball pitching performance can be mechanically explained by the summation of speed principle and the principle of optimal coordination of partial momenta. Impeding optimal energy generation or transfer by or between the pelvis and trunk segments could provide valuable insight into possible compensation or catch-up mechanisms...

journal article 2022

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Augmented reality navigation for minimally invasive craniosynostosis surgery: a phantom study

Thabit, Abdullah (author), Benmahdjoub, Mohamed (author), van Veelen, Marie Lise C. (author), Niessen, W.J. (author), Wolvius, Eppo B. (author), van Walsum, T. (author)

Purpose: In minimally invasive spring-assisted craniectomy, surgeons plan the surgery by manually locating the cranial sutures. However, this approach is prone to error. Augmented reality (AR) could be used to visualize the cranial sutures and assist in the surgery planning. The purpose of our work is to develop an AR-based system to...

journal article 2022

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Feasibility and validity of a single camera CNN driven musculoskeletal model for muscle force estimation during upper extremity strength exercises: Proof-of-concept

Noteboom, L. (author), Hoozemans, Marco J.M. (author), Veeger, H.E.J. (author), van der Helm, F.C.T. (author)

Muscle force analysis can be essential for injury risk estimation and performance enhancement in sports like strength training. However, current methods to record muscle forces including electromyography or marker-based measurements combined with a musculoskeletal model are time-consuming and restrict the athlete's natural movement due to...

journal article 2022

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Classification of Wheelchair Related Shoulder Loading Activities from Wearable Sensor Data: A Machine Learning Approach

de Vries, Wiebe H.K. (author), Amrein, Sabrina (author), Arnet, Ursina (author), Mayrhuber, Laura (author), Ehrmann, Cristina (author), Veeger, H.E.J. (author)

Shoulder problems (pain and pathology) are highly prevalent in manual wheelchair users with spinal cord injury. These problems lead to limitations in activities of daily life (ADL), labor- and leisure participation, and increase the health care costs. Shoulder problems are often associated with the long-term reliance on the upper limbs, and...

journal article 2022

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Electromyography-driven model-based estimation of ankle torque and stiffness during dynamic joint rotations in perturbed and unperturbed conditions

Cop, Christopher P. (author), Schouten, A.C. (author), Koopman, Bart (author), Sartori, Massimo (author)

The simultaneous modulation of joint torque and stiffness enables humans to perform large repertoires of movements, while versatilely adapting to external mechanical demands. Multi-muscle force control is key for joint torque and stiffness modulation. However, the inability to directly measure muscle force in the intact moving human prevents...

journal article 2022

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The effect of an occlusion-induced delay on braking behavior in critical situations: A driving simulator study

de Winter, J.C.F. (author), Saffarian, M (author), Senders, John W. (author)

Objective: To share results of an experiment that used visual occlusion for a new purpose: inducing a waiting time. Background: Senders was a leading figure in human factors. In his research on the visual demands of driving, he used occlusion techniques. Methods: In a simulator experiment, we examined how drivers brake for different levels of...

journal article 2022

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Management of displaced humeral surgical neck fractures in daily clinical practice: hanging does not re-align the fracture

Spek, Reinier W.A. (author), Hoogervorst, Lotje A. (author), Elias, Michaëla E.C. (author), Jaarsma, Ruurd L. (author), Veeger, H.E.J. (author), Doornberg, Job N. (author), Jutte, Paul C. (author), van den Bekerom, Michel P.J. (author)

Introduction: It is unclear if the collar and cuff treatment improve alignment in displaced surgical neck fractures of the proximal humerus. Therefore, this study evaluated if the neckshaft angle and extent of displacement would improve between trauma and onset of radiographically visible callus in non-operatively treated surgical neck...

journal article 2022

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Shoulder kinematics and muscle activity following latissimus dorsi transfer for massive irreparable posterosuperior rotator cuff tears in shoulders with pseudoparalysis

Gurnani, Navin (author), Willems, W. Jaap (author), van Deurzen, Derek F.P. (author), Weening, Alexander A. (author), Bouwer, Joran (author), Janssen, Thomas W.J. (author), Veeger, H.E.J. (author)

Background: The aim of this study was to evaluate the thoracohumeral (TH) and glenohumeral (GH) motion with muscle activity after latissimus dorsi transfer (LDT) in a shoulder with a massive irreparable posterosuperior rotator cuff tear (MIRT) and pseudoparalysis compared with the asymptomatic contralateral shoulder (ACS). Methods: We...

journal article 2022

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Obtaining wheelchair kinematics with one sensor only? The trade-off between number of inertial sensors and accuracy for measuring wheelchair mobility performance in sports

van Dijk, M.P. (author), van der Slikke, R.M.A. (author), Rupf, Rob (author), Hoozemans, Marco J.M. (author), Berger, Monique A.M. (author), Veeger, H.E.J. (author)

In wheelchair sports, the use of Inertial Measurement Units (IMUs) has proven to be one of the most accessible ways for ambulatory measurement of wheelchair kinematics. A three-IMU configuration, with one IMU attached to the wheelchair frame and two IMUs on each wheel axle, has previously shown accurate results and is considered optimal for...

journal article 2022