Engineered 3D Polymer and Hydrogel Microenvironments for Cell Culture Applications

The realization of biomimetic microenvironments for cell biology applications such as organ-on-chip, in vitro drug screening, and tissue engineering is one of the most fascinating research areas in the field of bioengineering. The continuous evolution of additive manufacturing techniques provides the tools to engineer these architectures at...

3D Printing for Repair Guide

This guide takes the reader through the 3D Printing for Repair (3DP4R) process. It consists of guidelines and tools to create a 3D printable version of spare parts needed for a product repair. 3D printing a spare part is more than just printing the original part. Instead, it is an iterative process in which the part is analysed, redesigned,...

Multifunctional implants Prevention is better than cure

Millions of people around the globe receive orthopedic implants every year. These implants help people to regain their mobility and contribute tremendously to improve the quality of life. However, a significant number of patients suffer from complications, such as implant associated infections (IAI) and aseptic loosening. The number of...

Biomimetic Approaches for the Design and Fabrication of Bone-to-Soft Tissue Interfaces

Bone-to-soft tissue interfaces are responsible for transferring loads between tissues with significantly dissimilar material properties. The examples of connective soft tissues are ligaments, tendons, and cartilages. Such natural tissue interfaces have unique microstructural properties and characteristics which avoid the abrupt transitions...

Auxeticity as a Mechanobiological Tool to Create Meta-Biomaterials

Mechanical and morphological design parameters, such as stiffness or porosity, play important roles in creating orthopedic implants and bone substitutes. However, we have only a limited understanding of how the microarchitecture of porous scaffolds contributes to bone regeneration. Meta-biomaterials are increasingly used to precisely engineer...