Feasibility study on the integration of a deep learning dose computation algorithm in an automated proton therapy treatment planning system

The dose computation algorithm, or dose engine, is one of the fundamental parts of radiotherapy treatment planning. These algorithms predict how the dose will be distributed inside the patient.<br/>Current dose engines are mainly based on either Monte Carlo simulations (MC) or pencil beam algorithms (PBA). MC being very precise, but relatively...

Treatment planning of intensity modulated proton therapy by using sparsity inducement for spot selection

In intensity modulated proton therapy (IMPT), patients are irradiated with small spots, that deliver a local dose to the tumor. The number of possible spots to choose from is virtually infinite, but practically limited, which requires a spot selection. This spot selection should result in an optimal treatment plan, i.e., to deliver a sufficient...