Multicomponent Mechanical Characterization of Atherosclerotic Human Coronary Arteries: An Experimental and Computational Hybrid Approach

Atherosclerotic plaque rupture in coronary arteries, an important trigger of myocardial infarction, is shown to correlate with high levels of pressure-induced mechanical stresses in plaques. Finite element (FE) analyses are commonly used for plaque stress assessment. However, the required information of heterogenous material properties of...

Optimizing drug delivery using non-uniform magnetic fields: A numerical study

A comprehensive computational model for simulating magnetic drug targeting was developed and extensively tested in a cylindrical geometry. The efficiency for particle capture in a specific magnetic field and geometry was shown to be dependent on a single dimensionless number. The effect of secondary flows, a non-Newtonian viscosity and...