A novel viral infection model to guide optimal mpox treatment

In 2022, worldwide mpox outbreaks have called attention to mpox virus infection and treatment opportunities using the drugs cidofovir and tecovirimat, which target different stages of in-host viral proliferation, respectively production and shedding. We propose a new model of in-host viral infection dynamics that distinguishes between the two...

An experimental validation of the polynomial curvature model: identification and optimal control of a soft underwater tentacle

The control possibilities for soft robots have long been hindered by the lack of accurate yet computationally treatable dynamic models of soft structures. Polynomial curvature models propose a solution to this quest for continuum slender structures. Nevertheless, the results produced with this class of models have been so far essentially...

Model-Reference Reinforcement Learning for Collision-Free Tracking Control of Autonomous Surface Vehicles

This paper presents a novel model-reference reinforcement learning algorithm for the intelligent tracking control of uncertain autonomous surface vehicles with collision avoidance. The proposed control algorithm combines a conventional control method with reinforcement learning to enhance control accuracy and intelligence. In the proposed...

Automated seismic acquisition geometry design for optimized illumination at the target: a linearized approach

In seismic exploration methods, imperfect spatial sampling at the surface causes a lack of illumination at the target in the subsurface. The hampered image quality at the target area of interest causes uncertainties in reservoir monitoring and production, which can have a substantial economic impact. Especially in the case of a complex...

Selecting Informative Data Samples for Model Learning Through Symbolic Regression

Continual model learning for nonlinear dynamic systems, such as autonomous robots, presents several challenges. First, it tends to be computationally expensive as the amount of data collected by the robot quickly grows in time. Second, the model accuracy is impaired when data from repetitive motions prevail in the training set and outweigh...

Dual-axis manual control: Performance degradation, axis asymmetry, crossfeed, and intermittency

Vehicle control tasks require simultaneous control of multiple degrees-of-freedom. Most multi-axis human-control modeling is limited to the modeling of multiple fully independent single axes. This paper contributes to the understanding of multi-axis control behavior and draws a more realistic and complete picture of dual-axis manual control....

Effects of Linear Perspective on Human Use of Preview in Manual Control

Due to linear perspective, the visual stimulus provided by a previewed reference trajectory reduces with increasing distance ahead. This paper investigates the effects of linear perspective on human use of preview in manual control tasks. Results of a human-in-the-loop tracking experiment are presented, where the linear perspective&#x0027...