Searched for: subject%3A%22microfluidics%22
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Kawasaki, S. (author)
CMUTs (Capacitive Micromachined Ultrasonic Transducers) are causing a technological revolution. Research over the last decade showed that CMUTs can sufficiently replace traditional ultrasound technology based on the bulk PZT, along with other benefits such as lower assembly cost, broader bandwidth and monolithic integration capability with ASICs...
doctoral thesis 2024
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Neves Sao Pedro, M. (author)
Continuous biomanufacturing is considered the future phase for the optimization of production processes in the biopharmaceutical industry. Productivity, product quality and consistency are greatly improved while production costs and environmental footprint are drastically reduced. The manufacturing of monoclonal antibodies (mAbs), an important...
doctoral thesis 2023
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Motreuil-Ragot, P.A. (author)
An organ-on-chip (OoC) is a microelectromechanical (MEMS) device that aims to recapitulate in-vitro the physiology of the smallest functional unit of an organ in order to perform drug analysis or study disease models. OoCs are very complex systems that require actuation and sensing capabilities within controlled and delicate environment. The...
doctoral thesis 2023
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Muralidharan, A. (author)
Delivery of biomolecules using pulsed electric fields or electrotransfer has applications such as biomedical engineering, bioprocess engineering and genomic engineering. When a cell is placed in an electric field, the induced transmembrane voltage catalyzes the formation of pores on the cell membrane. This enables the delivery of otherwise cell...
doctoral thesis 2022
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Kislaya, A. (author)
The precise manipulation of particles and droplets is crucial to many microfluidic applications in engineering. The design of microfluidic devices is generally tailored to perform a specific task, with each specific application requiring a unique and fixed design. In this way, using a single device to perform multiple analyses of a wide range of...
doctoral thesis 2022
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Liu, Z. (author)
doctoral thesis 2022
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Totlani, K. (author)
A crucial challenge during the initial stages of bioprocess development is that tools used to screen microorganisms and optimize cultivation conditions do not represent the environment imposed at industrial scale. Inside an industrial-scale bioreactor, microorganisms are often cultivated under fed-batch conditions, where nutrients are supplied...
doctoral thesis 2021
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Büke, F. (author)
Bacteria have been an integral part of human life since the ancient times either as cooperative tenants living in and around us or as constant threats to our health and wellbeing. Since prehistoric times we unknowingly used them as tools of fermentation and fought against them with haphazardly discovered natural remedies. Today, after more than...
doctoral thesis 2020
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Fanalista, F. (author)
Cell replication is a fascinating biological process that ensures the proliferation of a species via division of a mother cell into two daughter ones. This process in bacteria is performed by a complex protein machinery named the Z-ring, which assembles at the cell mid-plane and promotes progressive membrane constriction down to division. A...
doctoral thesis 2020
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Sachdev, S. (author)
doctoral thesis 2020
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Mytnyk, S. (author)
Growing importance of hydrogels in various areas of human life has led to increasing need in controlling their properties, which is generally achieved by adjusting hydrogels shape and microstructure. Even though standard microfabrication and microstructuring techniques can be currently applied in hydrogel research, the variety of properties of...
doctoral thesis 2019
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Bui, T.H. (author)
The thesis focuses on the investigation of thin-film surface acoustic wave (SAW) devices for liquid sensing applications. The piezoelectric material is a thin film of Aluminum Nitride (AlN), a CMOS compatible material, deposited by pulse DC reactive sputtering technique. A CMOS compatible process is developed and employed to fabricate the AlN/Si...
doctoral thesis 2018
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Marin Lizarraga, V.M. (author)
This thesis presents a reliable technology to assemble free standing lipid membranes using microfabricated devices. A microfluidic cartridge consisting of parallel channels connected with a rectangular aperture was designed and characterized to assemble artificial membranes. This methodology resulted on a system capable of assembling lipid...
doctoral thesis 2018
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Kawale, D. (author)
Crude oil has been an important source of energy for several decades now. Upon discovery of a crude oil reservoir until its abandonment, typically the oil recovery process can be classified in three stages. The primary and the secondary stage involve utilizing and maintaining reservoir pressure to recover oil respectively. The tertiary, or the...
doctoral thesis 2017
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Tiruvadi Krishnan, S. (author)
All living organisms pass on their genetic information to their offspring in the form of DNA or RNA molecules by duplicating them across generations. In the bacteria, their genes are packed in long chains of DNA molecules or chromosomes. One of the widely studied model organisms, Escherichia coli, replicates its circular chromosome in two...
doctoral thesis 2016
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De Martino, M. (author)
doctoral thesis 2016
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Gude, S. (author)
Quantitative experiments with the ability to systematically probe the system under investigation are a key element to gain insight and understanding. We present a novel and simple technique enabling the maintenance and controlled perturbation of experimental conditions of microorganisms from bacteria to nematodes. Polyacrylamide-based devices...
doctoral thesis 2016
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Wu, F. (author)
One of the most basic features that pervade biology is the existence of boundaries that separate living cells from their outer environments. Molecules responsible for the internal organization of a living cell must adapt to its boundaries, as the cell grows, divides, and changes in shape and size. In this thesis, we aim to understand how...
doctoral thesis 2015
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Perez Garza, H.H. (author)
Properties of matter at the nano-scale may be very different from the ones observed at the macro-scale. The continuous variation of characteristics with diminishing size results in relevant changes in behavior. Similarly, these changes are caused by the rise of completely new phenomena (i.e. quantum confinement). Nanoscience can offer an...
doctoral thesis 2015
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Boulineau, S. (author)
doctoral thesis 2013
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