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Müller, M. (author), Schins, J.M. (author), Wurpel, G.W.H. (author)In multiplex CARS microscopy the generated anti-Stokes signal is generated and detected simultaneously over a significant part of the vibrational spectrum. The signal-to-noise ratio of the thus detected spectra is limited only by shot-noise. This principle is demonstrated using a dilution series of 2-propanol in water. It is derived...conference paper 2004
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Docter, M.W. (author), Young, I.T. (author), Kutchoukov, V.G. (author), Bossche, A. (author), Alkemade, P.F.A. (author), Garini, Y. (author)When light passes through a hole smaller than the wavelength of the light, the transmission is very low and the light is diffracted. This however changes if holes are arranged in a periodic array on metal. In that case the light couples to surface plasmons; this results in enhanced transmission, spectral selection and a small angular diffraction...conference paper 2005
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Van der Velde, O. (author), Copuroglu, O. (author), Veer, F.A. (author)This paper shows the benefit of using transmitted light microscopy together with a Z-scanning software in fractographical analyses of glass. The strength of glass is largely dependent on processes that happen at the microscale. In this research, 52 plates were fractured in a biaxial tensile test. These were divided into five categories according...conference paper 2015
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Docter, M.W. (author), Young, I.T. (author), Piciu, O. (author), Bossche, A. (author), Alkemade, P.F.A. (author), Van de Berg, P.M. (author), Garini, Y. (author)The knowledge of the near-field of extra-ordinary transmission through hole-arrays is mostly theoretical; there is less experimental validation of the theory. We study the near-field properties by measuring fluorescent molecules that are immersed in a solution and their Brownian motion. The measurements are performed by filling the space above...conference paper 2006
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de Rooij, Mario R. (author), França de Mendonça Filho, F. (author)In this article a trip is taken to characterize concrete through its hardened cement paste based on its microstructure. Optical microscopy is coupled to advanced image analysis, as well as statistical data analysis to characterize heterogeneous concrete material. The article takes a closer look at the determination of the w/c ratio through the...conference paper 2017
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Wilding, D. (author), Pozzi, P. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)Aberrations, scattering and absorption degrade the performance light-sheet fluorescence microscopes (LSFM). An adaptive optics system to correct for these artefacts and to optimize the light-sheet illumination is presented. This system allows a higher axial resolution to be recovered over the field-of-view of the detection objective. It is...conference paper 2016
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Wilding, D. (author), Pozzi, P. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Fiolka, Reto (author), Verhaegen, M.H.G. (author)The light-sheet fluorescence microscopy is an excellent tool for the investigation of large three dimensional microscopy samples at the cellular level, however, the ability to resolve features is strongly affected by the presence of scattering and aberrations. These effects are two fold in light-sheet microscopy, as the illumination path...conference paper 2018
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Heyer, A. (author)Microbiologically influenced corrosion (MIC) is known to be a dangerous process in ship tanks due to its rapid and yet unpredictable occurrence, leading to extremely fast local corrosion, possibly jeopardizing the structural integrity, in a relatively short time. This project focuses on a fundamental understanding of MIC processes in ship...doctoral thesis 2013
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Van der Valk, N.C.J. (author)Terahertz (=1012 Hz) radiation is a form of electromagnetic radiation that is at this moment used rarely for imaging purposes. However, there are indeed reasons to assume that imaging with terahertz radiation could be very useful. First, many materials, such as paper, plastics and clothing are transparent for terahertz radiation, while they...doctoral thesis 2005
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Moolman, M.C. (author)Investigating DNA replication in live E. coli cells using fluorescence microscopy and microfluidics.doctoral thesis 2015
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- Bisschop, J. (author) doctoral thesis 2002
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Narváez, A.C. (author)Cathodoluminescence (CL), the excitation of light by an electron beam, has gained attention as an analysis tool for investigating the optical response of a structure, at a resolution that approaches that in electron microscopy, in the nanometer range. However, the application possibilities are limited because the use of transparent substrates,...doctoral thesis 2014
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Vermolen, B.J. (author)Cancer is one of the most well-known groups of diseases that finds its cause in cells having chromosomal aberrations. How and why these aberrations can occur is one of the most important questions asked in modern molecular biology. In the last decades it has become clear that gene regulation in the nucleus, where the chromosomes reside, is...doctoral thesis 2009
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Van Aken, R.H. (author)This thesis has discussed two electron microscopy applications that make use of ultra-thin foils: the tunnel junction emitter and the low-energy foil corrector. Both applications have in common that the electron beam is sent through the thin foil at low energy. Part of the electrons will scatter in the foil, thus causing a reduction of the...doctoral thesis 2005
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Maddalena, L. (author)Optogenetics is a powerful addition to the spectrum of techniques available in neuroscience to investigate neurophysiology and unravel how neural circuit structure is related to circuit function. This technique relies on introducing lightsensitive proteins or molecules as actuators to transduce an optical signal into a physiological perturbation...doctoral thesis 2022
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Bijster, R.J.F. (author)In this thesis a proof-of-principle demonstration is developed that uses the heat flux between a probe and a sample as a proxy for their separation. The proposed architecture uses a probe that consists of a bilayer cantilever with an attached sphere at its free end. The deflection of the cantilever that is caused by the heat input is measured...doctoral thesis 2021
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Wilding, D. (author)The goal of this thesis, called Physical and Computational Approaches to Aberration Correction In Fluorescence Microscopy, concerns itself with the development of new techniques to control adaptive fluorescence microscopes, so that they can adapt and image with increased resolution, contrast and speed inside complex three-dimensional biological...doctoral thesis 2018
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Antolović, I.M. (author)The aim of this research is to explore the potential advantages of SPAD imagers used in microscopy. An ideal microscopy detector requires high sensitivity (high quantum efficiency QE or photon detection probability PDP), photon counting operation, low noise (dark current or dark count rate), timing resolution in the order of 100 ps, frame rate...doctoral thesis 2018
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- Docter, M.W. (author), Van den Berg, P.M. (author), Alkemade, P.F.A. (author), Kutchoukov, V.G. (author), Piciu, O.M. (author), Bossche, A. (author), Young, I.T. (author), Garini, Y. (author) journal article 2007
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Goetz, W. (author), Pike, W.T. (author), Hviid, S.F. (author), Madsen, M.B. (author), Morris, R.V. (author), Hecht, M.H. (author), Staufer, U. (author), Leer, K. (author), Sykulska, H. (author), Hemmig, E. (author), Marshall, J. (author), Morookian, J.M. (author), Parrat, D. (author), Vijendran, S. (author), Bos, B.J. (author), El Maarry, M.R. (author), Keller, H.U. (author), Kramm, R. (author), Markiewicz, W.J. (author), Drube, L. (author), Blaney, D. (author), Arvidson, R.E. (author), Bell, J.F. (author), Reynolds, R. (author), Smith, P.H. (author), Woida, P. (author), Woida, R. (author), Tanner, R. (author)The optical microscope onboard the Phoenix spacecraft has returned color images (4 ?m pixel?1) of soils that were delivered to and held on various substrates. A preliminary taxonomy of Phoenix soil particles, based on color, size, and shape, identifies the following particle types [generic names in brackets]: (1) reddish fines, mostly unresolved...journal article 2010
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