Performance Evaluation of AiDx assist in the diagnosis of Lymphatic Filariasis (LF) in field settings: A field study conducted by the INSPiRED NWO Project - Dec.2021

Development of DNA diagnostics of neglected tropical diseases in resource-limited settings

The aim of this thesis was to develop a DNA-detection scheme for a point-of-care diagnostic test for Neglected Tropical Diseases (NTDs) for use within resource-limited settings. The scientific innovation is to develop an adaptable DNA-detection scheme, using CRISPR-dCas9 (catalytically inactive Cas9), that can detect the DNA of any pathogen in...

Individual preferences in security risk decision making: an exploratory study under security professionals

Risk assessments in the (cyber) security domain are often, if not always, based on subjective expert judgement. For the first time, to the best of our knowledge, the individual preferences of professionals from the security domain are studied. In on online survey they are asked to mention, rate and rank their preferences when assessing a...

Meshworks of Care

Austerity and high land values in London have seen space for care minimised, privatised and restricted for efficiency and maximum profit. This project argues that care within architecture needs to be reclaimed from the closed practices that are framing it, and inhabited in its multiplicity. This work is situated in the neighbourhood of Wood...

Target product profiles for devices to diagnose urinary schistosomiasis in Nigeria

Schistosomiasis is a treatable and preventable neglected tropical disease of Public Health importance affecting over 200 million people worldwide while Nigeria is one of the high burden countries. Currently, available diagnostic tests are cumbersome, low in sensitivity and not field-adaptable given the high skills required that are not available...

The embodiment of low-field MRI for the diagnosis of infant hydrocephalus in Uganda

Compared to other parts of the world, the incidence of hydrocephalus in children is very high in sub- Saharan Africa. Magnetic resonance imaging (MRI) would be the preferred diagnostic method for infant hydrocephaleus. However, in practice, MRI is seldom used in sub-Saharan Africa due to its high prize, low mobility, and...

Improving access to diagnostics for schistosomiasis case management in oyo state, Nigeria: Barriers and opportunities

Schistosomiasis is one of the Neglected Tropical Diseases that affects over 200 million people worldwide, of which 29million people in Nigeria. The principal strategy for schistosomiasis in Nigeria is a control and elimination program which comprises a school-based Mass Drug Administration (MDA)with limitations of high re-infection rates and...

The Smart Optical Diagnostic of Schistosomiasis

Urinary schistosomiasis is with over 110 million infected people one of the most common parasitic infections worldwide, most commonly found in Sub-Saharan Africa. Urinary schistosomiasis is caused by the Schistosoma Haematobium (SH) parasite. The most common diagnostic method is manual microscopy, in which urine is manually examined to see...

Explore the untapped digital data of neglected tropical disease, and provide insights for stakeholders to take strategic actions

People have been using the digital technology domain to seek solutions to combat neglected tropical diseases. Aside from feasibility and effectiveness, WHO has pointed out the importance of having an overview that pinpoints the lacking infrastructure for scaling up and sustaining digital proposals. This research demystifies the untapped digital...

African Market: Entry for a Trypanosomiasis Diagnostic Device

This report is the result of a graduation project in the domain of the Africa Market Entry for a Trypanosomiasis Diagnostic Device. The project aims to find promising ways to bring to the market a portable diagnostic device for Trypanosomiasis, developed by the company Aidx Medical BV. The context of T. African Animal Trypanosomiasis (AAT) is a...

Diagnostics for Visceral Leishmaniasis in low resource settings within East Africa

This report is the result of a graduation project in the domain of the Neglected Tropical Disease (NTD): Visceral Leishmaniasis (VL) in low resource settings in East Africa. The project aims to find promising ways to fit a technical principle, which is being developed at the TUDelft, in the context of VL. VL endemic regions in Eastern Uganda and...