NEO: NEuro-Inspired Optimization—A Fractional Time Series Approach

Solving optimization problems is a recurrent theme across different fields, including large-scale machine learning systems and deep learning. Often in practical applications, we encounter objective functions where the Hessian is ill-conditioned, which precludes us from using optimization algorithms utilizing second-order information. In this...

Infrastructure maintenance and replacement optimization under multiple uncertainties and managerial flexibility

Infrastructure maintenance and replacement decisions are subject to uncertainties such as regular asset degradation, structural failure, and price uncertainty. In the engineering domain, Markov Decision Processes (MDPs) typically focus on uncertainties regarding asset degradation and structural failure. While the literature in the engineering...

Averaging Level Control to Reduce Off-Spec Material in a Continuous Pharmaceutical Pilot Plant

The judicious use of buffering capacity is important in the development of future continuous pharmaceutical manufacturing processes. The potential benefits are investigated of using optimal-averaging level control for tanks that have buffering capacity for a section of a continuous pharmaceutical pilot plant involving two crystallizers, a...

Sequential robust optimization of a V-bending process using numerical simulations

The coupling of finite element simulations to mathematical optimization techniques has contributed significantly to product improvements and cost reductions in the metal forming industries. The next challenge is to bridge the gap between deterministic optimization techniques and the industrial need for robustness. This paper introduces a...

Event-based progression detection strategies using scanning laser polarimetry images of the human retina

Monitoring glaucoma patients and ensuring optimal treatment requires accurate and precise detection of progression. Many glaucomatous progression detection strategies may be formulated for Scanning Laser Polarimetry (SLP) data of the local nerve fiber thickness. In this paper, several strategies, all based on repeated GDx VCC SLP measurements,...