Articulated Whole-Body Atlases for Small Animal Image Analysis: Construction and Applications

Purpose Using three publicly available small-animal atlases (Sprague–Dawley rat, MOBY, and Digimouse), we built three articulated atlases and present several applications in the scope of molecular imaging. Procedures Major bones/bone groups were manually segmented for each atlas skeleton. Then, a kinematic model for each atlas was built: each...

Atlas-driven scan planning for high-resolution Micro-SPECT data acquisition based on multi-view photographs: A pilot study

Highly focused Micro-SPECT scanners enable the acquisition of functional small animal data with very high-resolution. To acquire a maximum of emitted photons from a specific structure of interest and at the same time minimize the required acquisition time, typically only a small subvolume of the animal is scanned that contains the organs of...

Atlas-driven scan planning for high-resolution micro-SPECT data acquisition based on multi-vew photographs: A pilot study

Highly focused Micro-SPECT scanners enable the acquisition of functional small animal data with very high-resolution. To acquire a maximum of emitted photons from a specific structure of interest and at the same time minimize the required acquisition time, typically only a small subvolume of the animal is scanned that contains the organs of...

Integrated visualization of multi-angle bioluminescence imaging and micro CT

This paper explores new methods to visualize and fuse multi-2D bioluminescence imaging (BLI) data with structural imaging modalities such as micro CT and MR. A geometric, back-projection-based 3D reconstruction for superficial lesions from multi-2D BLI data is presented, enabling a coarse estimate of the 3D source envelopes from the multi-2D BLI...