Computational Models That Matter During a Global Pandemic Outbreak: A Call to Action

The COVID-19 pandemic is causing a dramatic loss of lives worldwide, challenging the sustainability of our health care systems, threatening economic meltdown, and putting pressure on the mental health of individuals (due to social distancing and lock-down measures). The pandemic is also posing severe challenges to the scientific community, with...

Network-inference-based prediction of the COVID-19 epidemic outbreak in the Chinese province Hubei

At the moment of writing, the future evolution of the COVID-19 epidemic is unclear. Predictions of the further course of the epidemic are decisive to deploy targeted disease control measures. We consider a network-based model to describe the COVID-19 epidemic in the Hubei province. The network is composed of the cities in Hubei and their...

Network-based prediction of COVID-19 epidemic spreading in Italy

Initially emerged in the Chinese city Wuhan and subsequently spread almost worldwide causing a pandemic, the SARS-CoV-2 virus follows reasonably well the Susceptible–Infectious–Recovered (SIR) epidemic model on contact networks in the Chinese case. In this paper, we investigate the prediction accuracy of the SIR model on networks also for...

Ethics of digital contact tracing and COVID-19: who is (not) free to go?

Digital tracing technologies are heralded as an effective way of containing SARS-CoV-2 faster than it is spreading, thereby allowing the possibility of easing draconic measures of population-wide quarantine. But existing technological proposals risk addressing the wrong problem. The proper objective is not solely to maximise the ratio of...

Pandemic programming: How COVID-19 affects software developers and how their organizations can help

Context: As a novel coronavirus swept the world in early 2020, thousands of software developers began working from home. Many did so on short notice, under difficult and stressful conditions.<br/><br/>Objective: This study investigates the effects of the pandemic on developers’ wellbeing and productivity.<br/><br/>Method: A questionnaire survey...

A Rapidly Deployable Test Suite for Respiratory Protective Devices in the COVID-19 Pandemic

Introduction: The current COVID-19 pandemic has caused large shortages in personal protective equipment, leading to hospitals buying their supplies from alternative suppliers or even reusing single-use items. Equipment from these alternative sources first needs to be tested to ensure that they properly protect the clinicians that depend on...

Responsible innovation in synthetic biology in response to COVID-19: the role of data positionality

Synthetic biology, as an engineering approach to biological systems, has the potential to disruptively innovate the development of vaccines, therapeutics, and diagnostics. Data accessibility and differences in data-usage capabilities are important factors in shaping this innovation landscape. In this paper, the data that underpin synthetic...

NOx Emissions Reduction and Rebound in China Due to the COVID-19 Crisis

During the COVID-19 lockdown (24 January–20 March) in China low air pollution levels were reported in the media as a consequence of reduced economic and social activities. Quantification of the pollution reduction is not straightforward due to effects of transport, meteorology, and chemistry. We have analyzed the NO_x emission...