This thesis aims to contribute to the definition of a comprehensive and integrated vision for Bogotá, Colombia, in terms of urban regeneration and social cohesion. It attempts to facilitate the construction of civic meaning, institutional cooperation and spatial revitalization in a historically unequal territory. By analyzing and recognizing the disparity between Bogotá’s urban transport and urban structure city models at the metropolitan level, this project will revise the impact and influence that past and prospective public transport systems could raise in the existing urban patterns and social dynamics of the Historic City Center. The objective is to redefine regeneration through mobilization in order to renegotiate the role that mobility structures could have as instruments for sustainable and inclusive socio-spatial transformations. The outlines are established under a systematized urban regeneration model engaged by the potentialities of a Sustainable Transit-Oriented Development. By providing an integrated framework, strategy and guidelines of this project will become an operative design platform able to promote new urban conditions and new forms of the state in the social, spatial and economic domain. The articulation between the values of mobility, identity and urban networks, from the local to the metropolitan level, will promote the consolidation of the City Center as the city’s main structural element once again. As a result, this will become a stepping stone for a competitive, genuinely democratic and socially-fair emerging metropolis model.