The integration of circular economy-based life cycle management (LCM) into product design and optimisation is essential for the transformation towards a circular economy (CE). However, companies often lack the expertise to adapt life-cycle design (LCD) thinking in their business operations and are in need of respective capacity building. To close this apparent gap is the aim of the project e-CirP (Embedding Circular Economy into Product Design and Optimization) where LUT University, Fraunhofer, Technical University of Denmark, University of Padova, Delft University of Technology, University of Helsinki and Metso Outotec have worked together to develop a program that allows Master students across Europe to learn how to integrate CE and Life Cycle Thinking principles into product design by analysing real industrial cases. In the project, modern pedagogical approaches have been applied. A modular training package covering general circular economy aspects, as well as detailed value chain perspectives, has been created. Next to the content-related aspects, a great focus was also on the support of so-called soft-skills development, e.g. through international student cooperation on case studies. The paper presents the perspective of participating students as well as the cooperating companies that supplied the industry cases to allow an overview of opportunities and challenges.@en

A deterministic population dynamics model involving birth and death for a two-species system, comprising a wild-type and more resistant species competing via logistic growth, is subjected to two distinct stress environments designed to mimic those that would typically be induced by temporal variation in the concentration of a drug (antibiotic or chemotherapeutic) as it permeates through the population and is progressively degraded. Different treatment regimes, involving single or periodical doses, are evaluated in terms of the minimal population size (a measure of the extinction probability), and the population composition (a measure of the selection pressure for resistance or tolerance during the treatment). We show that there exist timescales over which the low-stress regime is as effective as the high-stress regime, due to the competition between the two species. For multiple periodic treatments, competition can ensure that the minimal population size is attained during the first pulse when the high-stress regime is short, which implies that a single short pulse can be more effective than a more protracted regime. Our results suggest that when the duration of the high-stress environment is restricted, a treatment with one or multiple shorter pulses can produce better outcomes than a single long treatment. If ecological competition is to be exploited for treatments, it is crucial to determine these timescales, and estimate for the minimal population threshold that suffices for extinction. These parameters can be quantified by experiment.@en