Md
M. de Vries
Authored
5 records found
Steerable needles in prostate brachytherapy
From sketch to MDR-compliant batch
Brachytherapy (BT) is a safe and effective technique to treat prostate cancer that has not spread outside the prostate gland (localised prostate cancer). Nonetheless, in current clinical practice hazards can arise in positioning the BT needles in the prostate for the purpose of i
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Conformity of tumour volumes and dose plans in prostate brachytherapy (BT) can be constrained by unwanted needle deflections, needle access restrictions and visualisation limitations. This work validates the feasibility of teleoperated robotic control of an active steerable needl
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Microbrachytherapy with radioactive holmium-166 (166Ho) microspheres (MS) has the potential to be an effective treatment method for brain malignancies. Direct intratumoural delivery of 166Ho-MS and dose coverage of the whole tumour are crucial requirements. However, currently no
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Prostate cancer patients with an enlarged prostate and/or excessive pubic arch interference (PAI) are generally considered non-eligible for high-dose-rate (HDR) brachytherapy (BT). Steerable needles have been developed to make these patients eligible again. This study aims to val
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Steerable instruments allow for precise access to deeply-seated targets while sparing sensitive tissues and avoiding anatomical structures. In this study we present a novel omnidirectional steerable instrument for prostate high-dose-rate (HDR) brachytherapy (BT). The instrument u
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Contributed
7 records found
The Design of an Anthropomorphic Brain Phantom
Containing Ventricles
Brain, outside the body, will decay quickly, causing ex vivo studies to be difficult. Having a phantom model has a great beneficial value for numerous reasons. Phantoms are, among others, used in research centres, to validate new equipment, to develop biomechanical models or to t
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Minimally Invasive Sentinel Lymph Node Biopsy
Finding a less invasive alternative to an existing procedure
Sentinel lymph node biopsy (SLNB) is a procedure that is used to determine the stage of disease of melanoma patients and determine further treatment. However, the morbidities accompanied with this procedure are not negligible (e.g., wound infection, lymphoedema and seroma). With
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Design and Development of a prostate phantom model to mechanically mimic human tissue
To test new instruments developed for brachytherapy
Prostate cancer is the most frequently diagnosed type of cancer among males. Brachytherapy has become a common treatment for this disease. In this form of radiotherapy, sealed radiation sources are placed through a implant catheters inside the prostate. This treatment affects the
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The design of a brain and tumor phantom
Focused on mimicking the stiffness of the brain and glioblastoma multiforme tumor tissue
Glioblastoma multiforme tumors (GBM) are the most frequent and aggressive brain tumor type and have a very low survival rate. In order to improve the patient’s outcome for a patient suffering from GBM the production of brain phantoms can be of great help. A brain phantom can be u
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Prostate cancer is the most common cancer in men and third in terms of mortality. High dose rate brachytherapy is a common and effective treatment to treat this cancer. High dose rate brachytherapy requires the implantation of several needles into the prostate trough which a radi
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Prostate cancer is the most frequently diagnosed cancer type among men, and the third deathliest form of cancer. Several treatments are available to treat prostate cancer. Low Dose Rate Brachytherapy (LDR BT) is one of them, which inserts permanent radioactive seeds into the pros
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Breast cancer is currently the most prevalent type of cancer. The concluding diagnosis can be obtained with an MRI-guided biopsy. However, due to respiratory movement and human error, the procedure can require multiple attempts, resulting in harmful consequences. To reach the tar
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