The Nitrogen-Vacancy (NV) center has demonstrated great potential as a quantum networks platform. While many milestones have been reached, the current hardware implementations have reached their limit in terms of remote entanglement generation rates, which hinders the scalability of the platform. The most dominant limits are that only ∼ 3% of the emission is coherent, and the outcoupling efficiency in state-of-the-art network experiments is ∼ 15%. The coherent emission can be increased via the Purcell effect, which can be achieved by the use of an open Fabry-Pérot microcavity. In such a setup the NV center is embedded in a micrometer-thin diamond membrane, thereby retaining its favourable optical properties. The open microcavity has the ability of in situ spectral and spatial tunability. However, this is accompanied by a high susceptibility to vibrations, which needs to be considered in the experimental design. The goal of this thesis is to simultaneously increase the coherent emission and the outcoupling efficiency by coupling NV centers to an open Fabry-Pérot microcavity. An optimized cavity is found by characterizing different fiber tip mirrors, reaching a bare cavity finesse of 9500. The vibrations in the bare cavity are analyzed, revealing a root mean square cavity length detuning of 22 pm while operating at low temperature. A hybrid cavity is formed with a diamond membrane with NV centers, resulting in cavity with a finesse of 2100, quality factor of 266000, mode volume of 108 λ 3 , and outcoupling efficiency ∼ 30%. Due to a different setup configuration, an increased root mean square cavity length detuning of 190 pm is measured, resulting in a lowered Purcell factor. Off-resonant measurements demonstrate the coupling of NV centers to the cavity. Moreover, excited state lifetimes are measured to obtain a Purcell factor of 2.6 ± 0.5, with a corresponding enhanced coherent emission ratio of 0.07 ± 0.01. This result is in good agreement with simulations that include the effect of vibrations. The ZPL branching ratio and outcoupling efficiency are improved by a factor two compared to state-of-the-art confocal microscope setups. For the first time in open microcavities, the ability to drive the spin of NV centers is shown by an optically detected magnetic resonance measurement with a contrast of (28 ± 2)%. By improving the setup to the already obtained vibration level, and a realistic finesse of 5000, an expected Purcell factor of ∼ 15.7 and outcoupling efficiency of ∼ 80% can be reached, paving the way to the next-generation of quantum network nodes.