Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues

The thioesterase of the erythromycin-producing polyketide synthase: influence of acyl chain structure on the mode of release of substrate analogues from the acyl enzyme intermediates.

Evaluating precursor-directed biosynthesis towards novel erythromycins through in vitro studies on a biomodular polyketide synthase.