JB
Jorge Bonekamp
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We study predictive control for blood glucose regulation in patients with type 1 diabetes mellitus. We determine optimal control actions for insulin and glucagon infusion via linear time-varying model predictive control (LTV MPC) and dynamic linerization around the state trajectory predicted. Through in silico implementation of a comprehensive nonlinear model, we show that our proposed controller is able to reject meal disturbances, retain normoglycemia afterwards and significantly outperform standard linearized MPC.
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We study predictive control for blood glucose regulation in patients with type 1 diabetes mellitus. We determine optimal control actions for insulin and glucagon infusion via linear time-varying model predictive control (LTV MPC) and dynamic linerization around the state trajectory predicted. Through in silico implementation of a comprehensive nonlinear model, we show that our proposed controller is able to reject meal disturbances, retain normoglycemia afterwards and significantly outperform standard linearized MPC.