The nature of the Meuse River is more than any other major river in the Netherlands formed by the presence of weirs. These were constructed almost one century ago to enable transport of coal; nowadays, the boundary conditions have changed and will continue to change in the future. The weirs reach the end of their lifetime around 2030; during their replacement, the uncertain future has to be considered. This paper presents an adaptive river design, which is able to adapt to the changing requirements. Special attention is given to the design of an adaptive weir in the Meuse River to replace the present weir at Belfeld. A new design methodology has been developed and applied. The methodology results shown in an adaptation scheme, give an overview of the required regional and weir adaptations. These adaptations are required to serve the scenario-dependent purposes in the future.@en