This thesis comprises of vertical deformation differences in high-rise structures where a concrete stability core is combined with a timber frame. The timber frame consists out of prefab timber modules which derive all lateral stability from the concrete core. Due to contrasting elastic, hygroexpansion and viscoelastic properties there is a notable difference in the vertical deformation of the concrete core and the timber units. The impact of these deformations have been outlined and possibilities to minimize the impact have been explored in this thesis.