Responsible innovation considers the impact of a new process/product on society and the environment. It mainly refers to collaboration and communication between parties to obtain an ethically acceptable, sustainable, and socially desirable innovation. This study focuses on the factors influencing the implementing the RI framework, which consists of Anticipation, Inclusion, Reflexivity, and Responsiveness within start-ups. The following research question has been investigated: ‘’Which factors affect the implementation of Responsible Innovation dimensions in start-ups.’’