In the ever-changing landscape of the 21st century, complex issues like climate change demand holistic solutions. However, traditional scientific approaches often fall short by employing reductionism, breaking problems into isolated parts. This executive summary introduces a thesis that calls for a shift towards a more holistic and interdisciplinary perspective in the field of biotechnology. It outlines a three-phase research approach, seeking to cultivate a 'holistic' mindset within this academic discipline. Phase 1 explores contextual influences on inter- and transdisciplinary mindsets in biotechnology. By introducing unusual triggers, such as artworks, researchers induce shifts in participants' perspectives. Emotions and cognitive dissonance emerge as key drivers of change, emphasizing the role of context in shaping mindsets. Phase 2 delves into defining factors that continuously nurture a 'holistic' mindset. It highlights the importance of preserving individuality while fostering connections, utilizing boundary objects for effective communication, and leveraging emotions as triggers for reflective conversations. Phase 3 involves the design of the "Out of Context!" tool, aimed at supporting interdisciplinary practices and the development of a 'holistic' mindset among biotechnology professionals. The tool is designed with criteria that ensure contextual relevance, creative discussions, integration of personal beliefs, support for minor interactions, and the establishment of a common ground. This research offers a novel approach to fostering interdisciplinary thinking in biotechnology and could inform the development of a 'holistic' mindset within the field. It emphasizes the need for practitioners and researchers to share their experiences, ultimately advancing interdisciplinary practices in biotechnology. The effective implementation and evaluation of the "Out of Context!" tool are crucial, as it has the potential to transform discussions within the field, furthering the practice of inter- and transdisciplinarity in biotechnology.