Fractional-order dynamical networks are increasingly being used to model and describe processes demonstrating long-term memory or complex interlaced dependencies among the spatial and temporal components of a wide variety of dynamical networks. Notable examples include networked control systems or neurophysiological networks which are created using electroencephalographic (EEG) or blood-oxygen-level-dependent data. As a result, the estimation of the states of fractional-order dynamical networks poses an important problem. To this effect, this article addresses the problem of minimum-energy state estimation for discrete-time fractional-order dynamical networks, where the state and output equations are affected by an additive noise that is considered to be deterministic, bounded, and unknown. Specifically, we derive the corresponding estimator and show that the resulting estimation error is exponentially input-to-state stable with respect to the disturbances and to a signal that is decreasing with the increase of the accuracy of the adopted approximation model. An illustrative example shows the effectiveness of the proposed method on real-world neurophysiological networks. Our results may significantly contribute to the development of novel neurotechnologies, particularly in the development of state estimation paradigms for neural signals such as EEG, which are often noisy signals known to be affected by artifacts not having any particular stochastic characterization.

Neurotechnology has made great strides in the last 20 years. However, we still have a long way to go to commercialize many of these technologies as we lack a unified framework to study cyber-neural systems (CNS) that bring the hardware, software, and the neural system together. Dynamical systems play a key role in developing these technologies as they capture different aspects of the brain and provide insight into their function. Converging evidence suggests that fractional-order dynamical systems are advantageous in modeling neural systems because of their compact representation and accuracy in capturing the long-range memory exhibited in neural behavior. In this brief survey, we provide an overview of fractional CNS that entails fractional-order systems in the context of CNS. In particular, we introduce basic definitions required for the analysis and synthesis of fractional CNS, encompassing system identification, state estimation, and closed-loop control. Additionally, we provide an illustration of some applications in the context of CNS and draw some possible future research directions. Advancements in these three areas will be critical in developing the next generation of CNS, which will, ultimately, improve people's quality of life.

Discrete-time fractional-order dynamical systems (DT-FODS) have found innumerable applications in the context of modeling spatiotemporal behaviors associated with long-term memory. Applications include neurophysiological signals such as electroencephalogram (EEG) and electrocorticogram (ECoG). Although learning the spatiotemporal parameters of DT-FODS is not a new problem, when dealing with neurophysiological signals we need to guarantee performance standards. Therefore, we need to understand the trade-offs between sample complexity and estimation accuracy of the system parameters. Simply speaking, we need to address the question of how many measurements we need to collect to identify the system parameters up to an uncertainty level. In this paper, we address the problem of identifying the spatial and temporal parameters of DT-FODS. The main result is the first result on non-asymptotic finite-sample complexity guarantees of identifying DT-FODS. Finally, we provide evidence of the efficacy of our method in the context of forecasting real-life intracranial EEG time series collected from patients undergoing epileptic seizures.

Solving optimization problems is a recurrent theme across different fields, including large-scale machine learning systems and deep learning. Often in practical applications, we encounter objective functions where the Hessian is ill-conditioned, which precludes us from using optimization algorithms utilizing second-order information. In this paper, we propose to use fractional time series analysis methods that have successfully been used to model neurophysiological processes in order to circumvent this issue. In particular, the long memory property of fractional time series exhibiting non-exponential power-law decay of trajectories seems to model behavior associated with the local curvature of the objective function at a given point. Specifically, we propose a NEuro-inspired Optimization (NEO) method that leverages this behavior, which contrasts with the short memory characteristics of currently used methods (e.g., gradient descent and heavy-ball). We provide evidence of the efficacy of the proposed method on a wide variety of settings implicitly found in practice.

Most optimization problems lack closed-form solutions of the argument that minimizes a given function, and even if these were available it might be prohibitive to compute it. As such, we rely on iterative numerical algorithms to find an approximate solution. In this paper, we propose to leverage fractional calculus in the context of time series analysis methods to devise a new iterative algorithm. Specifically, we propose to leverage autoregressive fractional-order integrative moving average time series, whose coefficients encode a proxy for local spatial information. We provide evidence that our algorithm is efficient and particularly suitable for cases where the Hessian is ill-conditioned.