By 2030, healthcare is expected to shift its focus toward harnessing the human body’s regenerative abilities to cure and eradicate chronic and genetic diseases, while enabling total recovery from severe accidents. As science and the healthcare industry transition from a “treat and repair” model to a “regenerate and restore” paradigm, hospital architecture will evolve to support the advancements in regenerative medicine.

This project is a deep exploration into the intersection of regenerative medicine and hospital architecture. It envisions a highly specialized hospital designed to treat patients by eradicating genetic and chronic diseases. The overarching idea of regeneration plays a central role in shaping the hospital’s program, site, and architectural design. This approach ensures that the hospital is tailored to meet the specific needs of human regeneration, aligning with cutting-edge scientific breakthroughs. The project integrates the four fundamental components of healthcare and regeneration under one roof: care, production, administration, and diagnosis/analysis, along with long-term storage facilities. This collaborative model creates a cohesive environment optimized for the process of regeneration. Simultaneously, the design prioritizes creating a sanctuary for patients and staff, while reimagining hospitals as vibrant, open public spaces that integrate seamlessly with the urban fabric and natural environment.

Ultimately, this project serves as a vision for how hospitals of the future can become not only centers of medical excellence but also community hubs that foster connection, healing, and innovation.

These days the goals of urban and territorial transformation are being tailored to make cities safer, healthier, and more centered on people in both developed and developing countries worldwide. While being an integral part of urban fabric from ages, public health agendas were traditionally treated as standalone from other policy areas. Nonetheless, the Covid-19 Pandemic has brought attention to the necessity of considering human health and including it into the planning of future cities in order to make them a safe place to live and to combat future pandemic scenarios. Public health and urban planning have always been intertwined, with modern urban planning emerging in the 19th century as a response to issues with inadequate sanitation, poor water supply, and air pollution. Due to their high population density and status as the continent’s most developed regions, metropolises have historically been the area’s most severely impacted by epidemics and other instances of widespread disease.

Every new pandemic, epidemic, or outbreak of a contagious disease reveals and targets a unique element of urban planning and architecture. This thesis explores how public health has been present throughout the history of urban planning and changes, examining the relationship between them and how it has impacted the transformation of the City of Amsterdam.