This study presents the development of a pro grammable microfluidic device designed for precise hydrodynamic manipulation of particles and fluids. Utilising femtosecond laser ablation and cold oxygen plasma bonding, the device features highly accurate microfluidic inlets with minimal surface rough ness, ensuring consistent flow dynamics. Experimental validation confirmed the device’s ability to generate uniform flow fields and half Rankine bodies, demonstrating its potential for real time reconfigurability in various applications, including particle manipulation and flow field analysis. The research lays the groundwork for future advancements in microfluidic technology, emphasising high precision and structural integrity.