East/West (E/W) vertical bifacial photovoltaic (PV) modules can achieve higher profits than the conventional North/South (N/S) tilted configuration depending on the design choices and external conditions. In this study a model based on 2D view factor concept is developed to estimate the power generated by a large-scale bifacial PV farm, considering the non-uniformity of the incident irradiance and the spectral impact. A validation using measured data is performed, focusing on the non-uniformity of the rear irradiance. This model is used to compare the profitability between E/W vertical and N/S tilted PV farm configurations, considering higher prices during noon with respect to morning/evening periods. The results identify the ratio between these two price values as the key variable that influences the comparison between the PV farm configurations. Specifically, a sufficiently high price ratio ensures the higher profitability of E/W vertical modules, however, the exact value is dependent on the location and the design variables. In general, higher row-to-row distance and lower diffuse fraction enhance the profitability of the E/W vertical over the N/S tilted configuration. On the other hand, elevation of the modules, curtailment strategies and hybrid solutions have a minor influence.@en