This interdisciplinary project developed a framework for implementing digital twins in European healthcare, focusing on secure, standardized data infrastructures and interoperable European Health Record (EHR) systems. It involved students from aerospace, strategic design, clinical medicine, and mechanical engineering. Analysis between Sweden and the Netherlands revealed Sweden excels in governance and trust, whereas the Netherlands is stronger in technical infrastructure. Overall adoption of digital twins is hindered by data privacy concerns and consent models. The public sector demonstrated the highest readiness, while patient groups showed lower willingness. The outcome includes an interactive dashboard, a readiness index, and an actionable implementation blueprint.