The Greenland Ice Sheet has a total volume of 2900000 km3. In recent decades, the ice-sheet has been losing mass rapidly and has nearly doubled its contribution to sea-level rise. One main contributing factor has been the recent widespread acceleration of the tidewater glaciers that terminate in deep and narrow glacial fjords. However, our understanding of the subsurface water properties causing this acceleration has been extremely limited owing to the lack of observations around these locations. We hypothesize that while the ice-sheet is not coupled to the ocean in the current General Circulation Models (GCMs), they can still be used to improve our understanding of the subsurface warming around these regions. In this study, we first evaluate two GCMs (HADGEM2-ES and GISS-E2-R) around three tidewater glacier locations, by interpolating the high resolution CTD data to the GCM grid. Our results substantiate that GISS-E2-R performs better than the HADGEM2-ES model along the Western Margin. However, along the Eastern Margin, we find that the HADGEM2-ES model is more consistent with the observations. The modelled spatio-temporal variability of water masses was investigated in a Pre-Industrial and Historical simulation, later used to quantify the evolution of subsurface warming under a future warming (RCP 8.5) scenario. Our results show that the Kangerlussuaq glacier (shelf) is more sensitive to greenhouse gas (GHG) forcings than Helheim and Jakobshavn. With respect to the Pre-Industrial climate, the mean warming of the Kangerlussuaq shelf under the RCP 8.5 scenario is 3.76°C, which is considerably greater than Helheim (2.38°C) and Jakobshavn (1.92°C). This is predominantly driven by the subsurface Return Waters of the Arctic Atlantic which are seen to warm the most under a future warming (RCP 8.5) scenario. For each of the three simulation, we decompose the Ocean Heat Content (OHC) time-series into intrinsic oscillatory modes so as to discern and quantify the high frequency variability from the multi-year/decadal variability and trends in the OHC. Where the contribution from the high-frequency modes to the total energy contained in the OHC signal is considerable in a Pre-Industrial scenario; the Historical and RCP 8.5 derived OHC are seen to contain a very dominant low-frequency response to GHG forcings, which contains (almost) all of the energy contained in the signal. For the RCP 8.5 scenario, we infer that at Kangerlussuaq, such a response is considerably greater than other locations. Furthermore, a consistent long-term increasing trend is seen in the upper ocean heat content for Kangerlussuaq, throughout the 21st century (1.01 × 10^8 J/m^2/month), unlike our inferences from other locations. This trend is found to be an order of magnitude higher than Helheim (2.36 × 10^7 J/m^2/month) and Jakobshavn (1.27 × 10^7 J/m^2/month). Our results also indicate that sea-ice free months at the Nares Strait (A.D. 2055 onwards) allows for a relatively greater mixing of the Lincoln Sea and Baffin Bay waters, which is consistent with the decline and stagnation of the rising OHC at Jakobshavn.