Adler, Benjamin A. (author), Trinidad, Marena I. (author), Bellieny-Rabelo, Daniel (author), Zhang, Elaine (author), Karp, Hannah M. (author), Skopintsev, Petr (author), Thornton, Brittney W. (author), Yoon, Peter H. (author), Brouns, S.J.J. (author) CRISPR-Cas enzymes enable RNA-guided bacterial immunity and are widely used for biotechnological applications including genome editing. In particular, the Class 2 CRISPR-associated enzymes (Cas9, Cas12 and Cas13 families), have been deployed for numerous research, clinical and agricultural applications. However, the immense genetic and...
journal article 2024