Point Forces and Their Alternatives in Cell-Based Models for Skin Contraction

Conference Paper (2021)
Author(s)

Qiyao Peng (TU Delft - Delft Institute of Applied Mathematics, TU Delft - Numerical Analysis)

Fred Vermolen (TU Delft - Numerical Analysis)

Research Group
Numerical Analysis
DOI related publication
https://doi.org/10.1007/978-3-030-55874-1_75 Final published version
More Info
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Publication Year
2021
Language
English
Research Group
Numerical Analysis
Pages (from-to)
763-771
Publisher
Springer
ISBN (print)
978-3-0305-5873-4
Event
European Conference on Numerical Mathematics and Advanced Applications, ENUMATH 2019 (2019-09-30 - 2019-10-04), Egmond aan Zee, Netherlands
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171

Abstract

We consider a cell-based approach in which the balance of momentum is used to predict the impact of cellular forces on the surrounding tissue. To this extent, the elasticity equation and Dirac Delta distributions are combined. In order to avoid the singularity caused by Dirac Delta distribution, alternative approaches are developed and a Gaussian distribution is used as a smoothed approach. Based on the application that the pulling force is pointing inward the cell, the smoothed particle approach is probed as well. In one dimension, it turns out that the aforementioned three approaches are consistent. For two dimensions, we report a computational consistence between the direct and smoothed particle approach.