Graphene nano-electromechanical mass sensor with high resolution at room temperature

Journal Article (2023)
Author(s)

Dong Hoon Shin (TU Delft - Dynamics of Micro and Nano Systems, Kavli institute of nanoscience Delft, Ewha Womans University)

Hakseong Kim (Korea Research Institute of Standards and Science, Daejon)

Sung Hyun Kim (Kavli institute of nanoscience Delft, TU Delft - BN/Chirlmin Joo Lab)

Hyeonsik Cheong (Sogang University)

Peter G. Steeneken (TU Delft - Dynamics of Micro and Nano Systems, Kavli institute of nanoscience Delft)

Chirlmin Joo (Ewha Womans University, TU Delft - BN/Chirlmin Joo Lab, Kavli institute of nanoscience Delft)

Sang Wook Lee (Ewha Womans University)

DOI related publication
https://doi.org/10.1016/j.isci.2023.105958 Final published version
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Publication Year
2023
Language
English
Issue number
2
Volume number
26
Article number
105958
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Abstract

The inherent properties of 2D materials—light mass, high out-of-plane flexibility, and large surface area—promise great potential for precise and accurate nanomechanical mass sensing, but their application is often hampered by surface contamination. Here we demonstrate a tri-layer graphene nanomechanical resonant mass sensor with sub-attogram resolution at room temperature, fabricated by a bottom-up process. We found that Joule-heating is effective in cleaning the graphene membrane surface, which results in a large improvement in the stability of the resonance frequency. We characterized the sensor by depositing Cr metal using a stencil mask and found a mass-resolution that is sufficient to weigh very small particles, like large proteins and protein complexes, with potential applications in the fields of nanobiology and medicine.