Magnetic actuator for mechanical stretching of cells in organs-on-chip
Z. Liao (TU Delft - Mechanical Engineering)
C. M. Boutry – Mentor (TU Delft - Electronic Components, Technology and Materials)
J Sietsma – Mentor (TU Delft - Team Kevin Rossi)
Pasqualina M Sarro – Coach (TU Delft - Electronic Components, Technology and Materials)
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Abstract
Organ-on-chip (OoC) is invented around 10 years ago which is used to do pre-clinical drug test without live animals. Physiological microenvironment of different cells can be mimicked in OoC. In order to better form of tissue in OoC, mechanical stimulation can offer through different ways including pneumatic, thermal, and electric stimulations. As another way to offer mechanical deformation, magnetic stimulation has high reacting speed and wireless operation.