Enabling actuation and sensing in organs-on-chip using electroactive polymers
Paul Motreuil-Ragot (TU Delft - Electrical Engineering, Mathematics and Computer Science)
Andres Hunt (TU Delft - Mechanical Engineering)
Danesh Kasi (Leiden University Medical Center)
Bruno Brajon (TU Delft - Electrical Engineering, Mathematics and Computer Science)
Arn M.J.M. van den Maagdenberg (Leiden University Medical Center)
Valeria Orlova (Leiden University Medical Center)
Max Mastrangeli (TU Delft - Electrical Engineering, Mathematics and Computer Science)
Lina Sarro (TU Delft - Electrical Engineering, Mathematics and Computer Science)
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Abstract
•Actuation has been succesfully performed for 2h30 with no side effects nor
delimination of the human tissue
•0.1 % strain has been achieved during the actutaion mode, close to the
strain experienced in vivo by vSMCs
•0.72 V/mm sensitivity has been shown on the sensing mode
•Batch fabrication and downscaling will be targetted in the near future
•Actual sensing of the cells’ contraction will be reserved for further work