Enabling actuation and sensing in organs-on-chip using electroactive polymers
Paul Motreuil-Ragot (TU Delft - Electronic Components, Technology and Materials)
Andres Hunt (TU Delft - Mechatronic Systems Design)
Danesh Kasi (Leiden University Medical Center)
Bruno Brajon (TU Delft - Electronic Components, Technology and Materials)
Arn M.J.M. van den Maagdenberg (Leiden University Medical Center)
Valeria Orlova (Leiden University Medical Center)
Max Mastrangeli (TU Delft - Electronic Components, Technology and Materials)
Lina Sarro (TU Delft - Electronic Components, Technology and Materials)
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Abstract
•Actuation has been succesfully performed for 2h30 with no side effects nor
delimination of the human tissue
•0.1 % strain has been achieved during the actutaion mode, close to the
strain experienced in vivo by vSMCs
•0.72 V/mm sensitivity has been shown on the sensing mode
•Batch fabrication and downscaling will be targetted in the near future
•Actual sensing of the cells’ contraction will be reserved for further work