Noninvasive Hemodynamic Monitoring

Left Ventricular Pressure-Volume Loop Reconstruction

Master thesis (2019)

Authors

A.L. Reddington Mechanical Engineering

Contributors

R. Dekker Electronic Components, Technology and Materials - EEMCS (supervisor 1)
J. Dankelman Medical Instruments & Bio-Inspired Technology - Mechanical, Maritime and Materials Engineering (supervisor 2)
M.A.P. Pertijs Electronic Instrumentation - EEMCS (supervisor 2)
Faculty
Mechanical Engineering
Copyright: © 2019 Aoibhinn Reddington
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Published Date

22-08-2019

Language

English

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Faculty

Mechanical Engineering

Abstract

Heart disease - already a leading cause of death in industrialized societies - is becoming more and more prevalent as society ages. With this increase, improvements in diagnosis and monitoring of heart disease are necessary. Current state-of-theart cardiac assessment techniques are invasive and too strenuous for heart disease patients. Therefore, there is a need for a noninvasive, fast, and mobile cardiac evaluation method. We propose the use of personalized lumped parameter models to simulate the circulatory system, so that left ventricular pressure can be estimated from left ventricular volume as acquired with 3D ultrasound imaging. Subsequently, the estimated pressure and the imaged left ventricular volume can be used to reconstruct pressure-volume loops, which are significantly indicative of cardiac health. As ultrasound is fast, not strenuous, and can be applied from the bedside, this method is suitable for critical care patients.