New frontiers in enzyme immobilisation

Robust biocatalysts for a circular bio-based economy

Review (2021)
Author(s)

R.A. Sheldon (TU Delft - BT/Biocatalysis, University of Witwatersrand)

Alessandra Basso (Purolite, Llantrisant)

Dean Brady (University of Witwatersrand)

Research Group
BT/Biocatalysis
Copyright
© 2021 R.A. Sheldon, Alessandra Basso, Dean Brady
DOI related publication
https://doi.org/10.1039/d1cs00015b
More Info
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Publication Year
2021
Language
English
Copyright
© 2021 R.A. Sheldon, Alessandra Basso, Dean Brady
Research Group
BT/Biocatalysis
Issue number
10
Volume number
50
Pages (from-to)
5850-5862
Reuse Rights

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Abstract

This tutorial review focuses on recent advances in technologies for enzyme immobilisation, enabling their cost-effective use in the bio-based economy and continuous processing in general. The application of enzymes, particularly in aqueous media, is generally on a single use, throw-away basis which is neither cost-effective nor compatible with a circular economy concept. This shortcoming can be overcome by immobilising the enzyme as an insoluble recyclable solid, that is as a heterogeneous catalyst. This journal is