Medical oxygen on-site

Master thesis developing a medical oxygen purifying system using PSA

Master Thesis (2025)
Author(s)

J.P.K. Schretlen (TU Delft - Mechanical Engineering)

Contributor(s)

T. J.H. Vlugt – Mentor (TU Delft - Engineering Thermodynamics)

M. van der Elst – Mentor (TU Delft - Medical Instruments & Bio-Inspired Technology)

Faculty
Mechanical Engineering
More Info
expand_more
Publication Year
2025
Language
English
Graduation Date
20-03-2025
Awarding Institution
Delft University of Technology
Programme
['Mechanical Engineering | Energy, Flow and Process Technology']
Faculty
Mechanical Engineering
Reuse Rights

Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.

Abstract

When COVID-19 hit the Western world, it exposed an already existing shortage of medical oxygen. This study focuses on designing an oxygen purifier capable of producing high-purity oxygen on-site using Pressure Swing Adsorption (PSA) technology. Although small-scale oxygen devices are available on the market, little public information exists about their dimensions and working conditions. This research fills this gap by making the design open source, providing a foundation for other technicians, particularly in the developing world, to implement on-site oxygen production, which is essential for surgical use. Building upon a previous multi-column project that achieved peak oxygen concentrations of 75%, this study develops and thoroughly tests a single-column system. By varying adsorption and desorption pressures, fluctuating mass flow, and different desorption times, a comprehensive overview of its performance is obtained. These results are integrated into a configuration scheme representing multiple single-column systems giving insights into the amount of columns and pumps necessary to meet a patients demand. Experimental results showed that for lithium-treated zeolite, an adsorption pressure of 2 bar is sufficient, as higher pressures do not significantly improve outlet concentration performance. During desorption, a substantial increase in oxygen concentration was observed when using 0.3 bar instead of 0.5 bar, with peak concentration differences of almost 20%. Desorption time also plays a significant role in both outlet concentration and the overall system configuration. It can be concluded that a single-column system does not meet the requirements to provide the necessary oxygen concentration for a patient. While peak concentrations of 70% were measured, achieving a sustained average of 70% would require higher peak concentrations. Future works should explore alternative setups, particularly those incorporating a recycling system to enhance oxygen concentration peaks.

Files

License info not available