Development and Characterization of an Endoscopic TOF PET System

The endoscopic time-of-flight (TOF) positron emission tomography (PET) concept has many advantages compared with the traditional PET system. It improves the image quality by delivering higher spatial resolution and enhancing the signal-to-noise ratio. Implementing the endoscopic TOF PET system in an ultrasonic probe requires an ultra-miniaturized optical sensor capable of detecting single and multiple photons with high timing resolution. Due to the extreme levels of miniaturization of the detector head, the large data throughput produced by the optical sensor, and the real-time data processing requirement, it is required to integrate a field programmable gate array (FPGA) with complex functions inside the detector head. This work presents the investigation, development, and characterization of the endoscopic TOF PET detector head. It describes in detail the development of the prototype, the study of data processing algorithms and the implementation of firmware on the probe FPGA. The algorithms and implementations of data readout, timestamps sorting and filtering, and time mark estimation with order statistics are of particular interest because of the use of a tiny and resource-limited FPGA in the probe. Finally, the characterizations and measurements on the system prototype are reported in this thesis.

Subject

time-of-flight
PET
data sorting
time mark estimator
timestamps
Endo-TOFPET-US
MD-SiPM
FPGA
TDC

To reference this document use:

http://resolver.tudelft.nl/uuid:2c8102fd-f54e-4f39-be12-19873a63fe6d

Embargo date

2015-09-01

Part of collection

Student theses

Document type

master thesis

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PDF		thesis.pdf		38.41 MB
PDF		thesis_tinggong_v6.0.pdf		38.41 MB

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