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A Biophysics Toolbox for Reliable Data Acquisition and Processing in Integrated Force-Confocal Fluorescence Microscopy
A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint
CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation
Characterizing single-molecule dynamics of viral RNA-dependent RNA polymerases with multiplexed magnetic tweezers
SMC complexes can traverse physical roadblocks bigger than their ring size
DNA replication origins retain mobile licensing proteins
Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers
High-throughput, high-force probing of DNA-protein interactions with magnetic tweezers
Essential validation methods for E. coli strains created by chromosome engineering
Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier
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