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van Kempen, S. E. (author), Khanbareh, H. (author), Groen, W.A. (author), Hol, J.M.A.M. (author), van der Zwaag, S. (author)A novel method based on the Virtual Particle Mori–Tanaka (VPMT) is developed to predict the effective electro-elastic properties, d<sub>33</sub> and g33, of structured piezoelectric particulate composites with improved accuracy by means of a single parameter related to the spatial distribution of imperfectly aligned rod-like PZT particles....journal article 2020
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Hol, F.J.H. (author), Whitesides, George M. (author), Dekker, C. (author)Habitat spatial structure has a profound influence on bacterial life, yet there currently are no low-cost equipment-free laboratory techniques to reproduce the intricate structure of natural bacterial habitats. Here, we demonstrate the use of paper scaffolds to create landscapes spatially structured at the scales relevant to bacterial ecology...journal article 2019
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- Girrbach, Fabian (author), Hol, Jeroen D. (author), Bellusci, Giovanni (author), Diehl, Moritz (author) conference paper 2017
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Hol, F.J.H. (author), Rotem, Or (author), Jurkevitch, Edouard (author), Dekker, C. (author), Koster, D. (author)Soil is a microenvironment with a fragmented (patchy) spatial structure in which many bacterial species interact. Here, we explore the interaction between the predatory bacterium Bdellovibrio bacteriovorus and its prey Escherichia coli in microfabricated landscapes. We ask how fragmentation influences the prey dynamics at the microscale and...journal article 2016
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Hol, F.J.H. (author), Hubert, A.W.R. (author), Dekker, C. (author), Keymer Vergara, J.E. (author)During antibiotic treatment, antibiotic concentration gradients develop. Little is know regarding the effects of antibiotic gradients on populations of nonresistant bacteria. Using a microfluidic device, we show that high-density motile Escherichia coli populations composed of nonresistant bacteria can, unexpectedly, colonize environments...journal article 2016
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Hol, F.J.H. (author), Galajda, P. (author), Woolthuis, R.G. (author), Dekker, C. (author), Keymer, J.E. (author)Background The spatial structure of a habitat can have a strong impact on community dynamics. Different experimental approaches exist to explore the effect of spatial structure on bacterial communities. To investigate the effect of ‘space’, a single implementation of spatial structure is often contrasted to bacterial community dynamics in well...journal article 2015
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Hol, F.J.H. (author), Voges, M.J. (author), Dekker, C. (author), Keymer, J.E. (author)Background: Antagonistic interactions mediated by antibiotics are strong drivers of bacterial community dynamics which shape biodiversity. Colicin production by Escherichia coli is such an interaction that governs intraspecific competition and is involved in promoting biodiversity. It is unknown how environmental cues affect regulation of the...journal article 2014
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Hol, F.J.H. (author)In this thesis, I describe experiments aimed at understanding bacterial population dynamics in ecosystems that are spatially structured at the micro-scale. We combine microfabrication and microfluidics to create synthetic ecosystems that have a complex yet well-defined geometry and chemical composition. Bacteria that inhabit such ecosystems can...doctoral thesis 2014
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Hol, B. (author), Daamen, T.A. (author)De financieringsmogelijkheden van stedelijke gebiedsontwikkeling zijn de laatste jaren sterk gekrompen. De aanpak van gebiedsgerichte projecten zijn hierdoor kleinschaliger en meer lokaal geworden. Initiatieven moeten in toenemende mate ‘van onderop’ komen, en beginnen vaak met de (her)ontwikkeling van één of enkele vastgoedobjecten. De...journal article 2014
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Van Vliet, S. (author), Hol, F.J.H. (author), Weenink, T. (author), Galajda, P. (author), Keymer, J.E. (author)Background Bacterial habitats, such as soil and the gut, are structured at the micrometer scale. Important aspects of microbial life in such spatial ecosystems are migration and colonization. Here we explore the colonization of a structured ecosystem by two neutrally labeled strains of Escherichia coli. Using time-lapse microscopy we studied the...journal article 2014
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Hol, F.J.H. (author), Galajda, P. (author), Nagy, K. (author), Woolthuis, R.G. (author), Dekker, C. (author), Keymer, J.E. (author)Cooperative organisms are ubiquitous in nature, despite their vulnerability to exploitation by cheaters. Although numerous theoretical studies suggest that spatial structure is critical for cooperation to persist, the spatial ecology of microbial cooperation remains largely unexplored experimentally. By tracking the community dynamics of...journal article 2013
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- Pagitz, M.E. (author), Hol, J.M.A.M. (author) patent 2012
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Männik, J. (author), Wu, F. (author), Hol, F.J.H. (author), Bisicchia, P. (author), Sherratt, D.J. (author), Keymer, J.E. (author), Dekker, C. (author)Cell division in typical rod-shaped bacteria such as Escherichia coli shows a remarkable plasticity in being able to adapt to a variety of irregular cell shapes. Here, we investigate the roles of the Min system and the nucleoid-occlusion factor SlmA in supporting this adaptation. We study “squeezed” E. coli in narrow nanofabricated channels...journal article 2012
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- Hol, D.D. (author) master thesis 2010
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- Hol, D.D. (author) master thesis 2010
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- Hol, D.D. (author) master thesis 2010
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- Hol, D.D. (author) report 2009
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- Hol, D.D. (author) report 2009
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- Hol, D.D (author), van Leeuwen, E.E. (author) report 2008
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- Hol, D.D. (author) report 2008
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