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de Vries, M. (author), Christianen, M. E.M.C. (author), Luthart, L. (author), de Vries, K. C. (author), Kolkman-Deurloo, I. K.K. (author), van den Dobbelsteen, J.J. (author)
Prostate cancer patients with an enlarged prostate and/or excessive pubic arch interference (PAI) are generally considered non-eligible for high-dose-rate (HDR) brachytherapy (BT). Steerable needles have been developed to make these patients eligible again. This study aims to validate the dosimetric impact and performance of steerable needles...
journal article 2024
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de Vries, M. (author), Wijntjes, M. (author), Sikorski, J. (author), Moreira, P. (author), van de Berg, N.J. (author), van den Dobbelsteen, J.J. (author), Misra, S. (author)
Conformity of tumour volumes and dose plans in prostate brachytherapy (BT) can be constrained by unwanted needle deflections, needle access restrictions and visualisation limitations. This work validates the feasibility of teleoperated robotic control of an active steerable needle using magnetic resonance (MR) for guidance. With this system,...
journal article 2023
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de Vries, M. (author), Klaassen, N. J.M. (author), Morsink, N. C. (author), van Nimwegen, S. A. (author), Nijsen, J. F.W. (author), van den Dobbelsteen, J.J. (author)
Microbrachytherapy with radioactive holmium-166 (166Ho) microspheres (MS) has the potential to be an effective treatment method for brain malignancies. Direct intratumoural delivery of 166Ho-MS and dose coverage of the whole tumour are crucial requirements. However, currently no dedicated instruments for controlled intratumoural delivery...
journal article 2021