Engineered biochemical cues of regenerative biomaterials to enhance endogenous stem/progenitor cells (ESPCs)-mediated articular cartilage repair

As a highly specialized shock-absorbing connective tissue, articular cartilage (AC) has very limited self-repair capacity after traumatic injuries, posing a heavy socioeconomic burden. Common clinical therapies for small- to medium-size focal AC defects are well-developed endogenous repair and cell-based strategies, including microfracture,...

Additive manufacturing of vascular stents

With the advancement of additive manufacturing (AM), customized vascular stents can now be fabricated to fit the curvatures and sizes of a narrowed or blocked blood vessel, thereby reducing the possibility of thrombosis and restenosis. More importantly, AM enables the design and fabrication of complex and functional stent unit cells that...

Deep Learning in Maritime Autonomous Surface Ships: Current Development and Challenges

Autonomous surface ships have become increasingly interesting for commercial maritime sectors. Before deep learning (DL) was proposed, surface ship autonomy was mostly model-based. The development of artificial intelligence (AI) has prompted new challenges in the maritime industry. A detailed literature study and examination of DL...

Advances on methane reforming in solid oxide fuel cells

With the demand for anticipated green hydrogen and power production, novel and upgraded catalytic processes are desired for more effective utilization of precious natural resources. Methane steam reforming is an advanced and matured technology for converting methane to hydrogen and syngas. As a renewable energy resource containing a large...

Functionalized Hydrogels for Articular Cartilage Tissue Engineering

Articular cartilage (AC) is an avascular and flexible connective tissue located on the bone surface in the diarthrodial joints. AC defects are common in the knees of young and physically active individuals. Because of the lack of suitable tissue-engineered artificial matrices, current therapies for AC defects, especially full-thickness AC...

Improving the Mechanical Properties of Additively Manufactured Micro-Architected Biodegradable Metals

Additively manufactured (AM) micro-architected biodegradable metals offer a unique combination of properties that are ideal for bone regeneration including biocompatibility, a fully interconnected porous structure, and the possibility to fully regenerate bony defects with native tissue upon biodegradation. Currently, the mechanical properties...

Additively Manufactured Absorbable Porous Metal Implants: Processing, Alloying and Corrosion Behavior

Treating large bone defects is still a clinical challenge without perfect solution, mainly due to the unavailability of suitable bone implants. Additively manufactured (AM) absorbable porous metals provide unparalleled opportunities to realize the challenging requirements for bone-mimetic implants. Firstly, multi-scale geometries of such...

New innovations in pavement materials and engineering: A review on pavement engineering research 2021

Sustainable and resilient pavement infrastructure is critical for current economic and environmental challenges. In the past 10 years, the pavement infrastructure strongly supports the rapid development of the global social economy. New theories, new methods, new technologies and new materials related to pavement engineering are emerging....

Additively manufactured biodegradable porous metals

Partially due to the unavailability of ideal bone substitutes, the treatment of large bony defects remains one of the most important challenges of orthopedic surgery. Additively manufactured (AM) biodegradable porous metals that have emerged since 2018 provide unprecedented opportunities for fulfilling the requirements of an ideal bone...