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Towards reusable building blocks for agent-based modelling and theory development

Berger, Uta (author), Bell, Andrew (author), Barton, C. Michael (author), Chappin, E.J.L. (author), Dreßler, Gunnar (author), Filatova, T. (author), Fronville, Thibault (author), Lee, Allen (author), van Loon, Emiel (author), Lorscheid, Iris (author), Meyer, Matthias (author), Müller, Birgit (author), Piou, Cyril (author), Radchuk, Viktoriia (author), Roxburgh, Nicholas (author), Schüler, Lennart (author), Troost, Christian (author), Wijermans, Nanda (author), Williams, Tim G. (author), Wimmler, Marie Christin (author), Grimm, Volker (author)

Despite the increasing use of standards for documenting and testing agent-based models (ABMs) and sharing of open access code, most ABMs are still developed from scratch. This is not only inefficient, but also leads to ad hoc and often inconsistent implementations of the same theories in computational code and delays progress in the...

journal article 2024

document

Statistical Analysis of SARS-CoV-2 Using Wastewater-Based Data of Stockholm, Sweden

Chekkala, Aashlesha (author), Atasoy, M. (author), Williams, Cecilia (author), Cetecioglu, Zeynep (author)

An approach based on wastewater epidemiology can be used to monitor the COVID-19 pandemic by assessing the gene copy number of SARS-CoV-2 in wastewater. In the present study, we statistically analyzed such data from six inlets of three wastewater treatment plants, covering six regions of Stockholm, Sweden, collected over an approximate year...

journal article 2023

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A flexible micro-randomized trial design and sample size considerations

Xu, Jing (author), Yan, Xiaoxi (author), Figueroa, C.A. (author), Williams, Joseph Jay (author), Chakraborty, Bibhas (author)

Technological advancements have made it possible to deliver mobile health interventions to individuals. A novel framework that has emerged from such advancements is the just-in-time adaptive intervention, which aims to suggest the right support to the individuals when their needs arise. The micro-randomized trial design has been proposed...

journal article 2023

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Spatial Temperature and Water Molar Concentration Measurements Using Thermal and Electrostrictive Ligs During Operation of a Swirl Burner at Pressure

Weller, Lee (author), Shah, Priyav (author), Giles, Anthony (author), De Domenico, F. (author), Morris, Steve (author), Williams, Benjamin A.O. (author), Hochgreb, Simone (author)

Laser-Induced Grating Spectroscopy (LIGS) was applied in a high-pressure combustion facility. Instantaneous (sub-μs), spatially resolved (within 5 mm) measurements of temperature and molar fractions of water were obtained using thermal and electrostrictive LIGS signals. Temperatures up to 1800 K and water molar fractions between 0.01 and 0.12...

conference paper 2023

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Using normalised difference infrared index patterns to constrain semi-distributed rainfall–runoff models in tropical nested catchments

Sriwongsitanon, Nutchanart (author), Jandang, Wasana (author), Williams, James (author), Suwawong, Thienchart (author), Maekan, Ekkarin (author), Savenije, Hubert (author)

A parsimonious semi-distributed rainfall–runoff model has been developed for flow prediction. In distribution, attention is paid to both the timing of the runoff and the heterogeneity of moisture storage capacities within sub-catchments. This model is based on the lumped FLEXL model structure, which has proven its value in a wide range of...

journal article 2023

document

Fourth Annual Workshop on A/B Testing and Platform-Enabled Learning Research

Ritter, Steve (author), Heffernan, Neil (author), Williams, Joseph Jay (author), Lomas, J.D. (author), Bicknell, Klinton (author), Roschelle, Jeremy (author), Motz, Ben (author), McNamara, Danielle (author), Baraniuk, Richard (author)

Learning engineering adds tools and processes to learning platforms to support improvement research. One kind of tool is A/B testing-common in large software companies and also represented academically at conferences like the Annual Conference on Digital Experimentation (CODE). A number of A/B testing systems focused on educational apps have...

conference paper 2023

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Ratings and experiences in using a mobile application to increase physical activity among university students: implications for future design

Figueroa, C.A. (author), Gomez-Pathak, Laura (author), Khan, Imran (author), Williams, Joseph Jay (author), Lyles, Courtney R. (author), Aguilera, Adrian (author)

University students have low levels of physical activity and are at risk of mental health disorders. Mobile apps to encourage physical activity can help students, who are frequent smartphone-users, to improve their physical and mental health. Here we report students’ qualitative feedback on a physical activity smartphone app with motivational...

journal article 2023

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The potential impact of human interventions at different scales in offshore wind farms to promote flat oyster (Ostrea edulis) reef development in the southern North Sea

ter Hofstede, R. (author), Williams, Gregory (author), van Koningsveld, M. (author)

Incorporation of ecology and ecosystem services into marine infrastructural developments has gained interest over the last decades. Growing attention is given to combine the massive roll-out of offshore wind farms in the North Sea with reinstating the once rich but nowadays nearly extinct European flat oyster (Ostrea edulis). However, the...

journal article 2023

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Third Annual Workshop on A/B Testing and Platform-Enabled Learning Research

Ritter, Steven (author), Heffernan, Neil (author), Williams, Joseph Jay (author), Lomas, J.D. (author), Motz, Ben (author), Basu Mallick, Debshila (author), Bicknell, Klinton (author), McNamara, Danielle (author), Kizilcec, Rene F. (author)

Learning engineering adds tools and processes to learning platforms to support improvement research. One kind of tool is A/B testing, which is common in large software companies and also represented academically at conferences like the Annual Conference on Digital Experimentation (CODE). A number of A/B testing systems focused on educational...

conference paper 2022

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High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers

Ouyang, Ruochen (author), Martins Costa, A.R. (author), Cassidy, C. Keith (author), Otwinowska, Aleksandra (author), Williams, Vera C.J. (author), Latka, Agnieszka (author), Stansfeld, Phill J. (author), Drulis-Kawa, Zuzanna (author), Brouns, S.J.J. (author)

The Klebsiella jumbo myophage ϕKp24 displays an unusually complex arrangement of tail fibers interacting with a host cell. In this study, we combine cryo-electron microscopy methods, protein structure prediction methods, molecular simulations, microbiological and machine learning approaches to explore the capsid, tail, and tail fibers of...

journal article 2022

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Developing a pan-European high-resolution groundwater recharge map – Combining satellite data and national survey data using machine learning

Martinsen, Grith (author), Bessiere, Helene (author), Caballero, Yvan (author), Koch, Julian (author), Collados-Lara, Antonio Juan (author), Mansour, Majdi (author), Sallasmaa, Olli (author), Pulido-Velazquez, David (author), Williams, Natalya Hunter (author), Zaadnoordijk, Willem (author), Stisen, Simon (author)

Groundwater recharge quantification is essential for sustainable groundwater resources management, but typically limited to local and regional scale estimates. A high-resolution (1 km × 1 km) dataset consisting of long-term average actual evapotranspiration, effective precipitation, a groundwater recharge coefficient, and the resulting...

journal article 2022

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Developing an Optical Microlever for Stable and Unsupported Force Amplification

Andrew, Philippa Kate (author), Raudsepp, Allan (author), Nock, Volker (author), Fan, D. (author), Williams, Martin A.K. (author), Staufer, U. (author), Avci, Ebubekir (author)

Optical micromachines have the potential to improve the capabilities of optical tweezers by amplifying forces and allowing for indirect handling and probing of specimens. However, systematic design and testing of micromachine performance is still an emerging field. In this work we have designed and tested an unsupported microlever, suitable for...

conference paper 2022

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Prospects for multi-omics in the microbial ecology of water engineering

McDaniel, Elizabeth A. (author), Wahl, S.A. (author), Ishii, Shun'ichi (author), Pinto, Ameet (author), Ziels, Ryan (author), Nielsen, Per Halkjær (author), McMahon, Katherine D. (author), Williams, Rohan B.H. (author)

Advances in high-throughput sequencing technologies and bioinformatics approaches over almost the last three decades have substantially increased our ability to explore microorganisms and their functions – including those that have yet to be cultivated in pure isolation. Genome-resolved metagenomic approaches have enabled linking powerful...

review 2021

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An EU Common Training Framework for Landscape Architecture addressing the current needs of society

Cipriani, L. (author), de Vries, Jeroen (author), Stauskis, Gintaras (author), Auweck, Fritz (author), Triboi, Roxana (author), Andreucci, Maria Beatrice (author), Cervera Alonso de Medina, Marina (author), Cancela d’ Abreu, Margarida (author), Freire, Maria (author), Carapinha, Aurora (author), a Conceição Castro, Maria (author), Del Pozo, Cristina (author), Deveikienė, Vaiva (author), Gunnlaugsson, Hermann Georg (author), Fekete, Albert (author), Fetzer, Ellen (author), Fabris, Luca (author), Fingerova, Radmila (author), Gazvoda, Davorin (author), Gkoltsiou, Aikaterini (author), Harmanescu, Mihaela (author), Kamenecki, Monika (author), Koscak Miocic-Stosic, Vesna (author), Melone, Antonella (author), Mertens, Elke (author), Meeres, Sophia (author), Ortacesme, Veli (author), Noortman, Adrian (author), Sárospataki, Máté (author), Stiles, Richard (author), Trolf, Norbert (author), Tóth, Attila (author), Tomic Reljic, Dora (author), Tudora, Ioana (author), Valdés Tejera, Esther (author), Valánszki, István (author), Weckman, Emilia (author), Williams, Tony (author), Tutundzic, Andreja (author), Lambertini, Anna (author), Mihova, Katinka (author), Muru, Toomas (author), Dam, Torben (author), Teqja, Zydi (author)

conference paper 2021

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Knickpoints and crescentic bedform interactions in submarine channels

Chen, Ye (author), Parsons, Daniel R. (author), Simmons, Stephen M. (author), Williams, Rebecca (author), Cartigny, Matthieu J.B. (author), Hughes Clarke, John E. (author), Stacey, Cooper D. (author), Hage, Sophie (author), Azpiroz Zabala, M. (author)

Submarine channels deliver globally important volumes of sediments, nutrients, contaminants and organic carbon into the deep sea. Knickpoints are significant topographic features found within numerous submarine channels, which most likely play an important role in channel evolution and the behaviour of the submarine sediment-laden flows ...

journal article 2021

document

A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

Joglekar, Anoushka (author), Prjibelski, Andreyi (author), Mahfouz, A.M.E.T.A. (author), Collier, Paul (author), Lin, Susan (author), Schlusche, Anna Katharina (author), Marrocco, Jordan (author), Williams, Stephen R. (author), Haase, Bettina (author)

Splicing varies across brain regions, but the single-cell resolution of regional variation is unclear. We present a single-cell investigation of differential isoform expression (DIE) between brain regions using single-cell long-read sequencing in mouse hippocampus and prefrontal cortex in 45 cell types at postnatal day 7 (www.isoformAtlas.com...

journal article 2021

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Second Workshop on Educational A/B Testing at Scale

Ritter, Steve (author), Heffernan, Neil (author), Williams, Joseph Jay (author), Lomas, J.D. (author), Bicknell, Klinton (author)

The emerging discipline of Learning Engineering is focused on putting into place tools and processes that use the science of learning as a basis for improving educational outcomes. An important part of Learning Engineering focuses on improving the effectiveness of educational software. In many software domains, A/B testing has become a...

conference paper 2021

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Compartmentalized cross-linked enzymatic nano -aggregates (c -CLE n A) for efficient in-flow biocatalysis

De Martino, M. Teresa (author), Tonin, F. (author), Yewdall, N. Amy (author), Abdelghani, Mona (author), Williams, David S. (author), Hanefeld, U. (author), Rutjes, Floris P.J.T. (author), Abdelmohsen, Loai K.E.A. (author), Van Hest, Jan C.M. (author)

Nano-sized enzyme aggregates, which preserve their catalytic activity are of great interest for flow processes, as these catalytic species show minimal diffusional issues, and are still sizeable enough to be effectively separated from the formed product. The realization of such catalysts is however far from trivial. The stable formation of a...

journal article 2020

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4D objects-by-change: Spatiotemporal segmentation of geomorphic surface change from LiDAR time series

Anders, K.P. (author), Winiwarter, Lukas (author), Lindenbergh, R.C. (author), Williams, Jack G. (author), Vos, S.E. (author), Höfle, Bernhard (author)

Time series of topographic data are becoming increasingly widespread for monitoring geomorphic activity. Dense 3D time series are now obtained by near-continuous terrestrial laser scanning (TLS) installations, which acquire data at high frequency (e.g. hourly) and over long periods. Such datasets contain valuable information on topographic...

journal article 2020

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Design of optical micromachines for use in biologically relevant environments

Andrew, Philippa Kate (author), Fan, D. (author), Raudsepp, Allan (author), Lofroth, Matthew (author), Staufer, U. (author), Williams, Martin A.K. (author), Avci, Ebubekir (author)

Advances in nanofabrication over the past twenty years have enabled the creation and use of ever-more interesting and useful micromachines. Optical micromachines are a particularly attractive subset of these for researchers in biological and soft-matter sciences, due to their potential to aid in optical tweezer studies of laser-sensitive...

conference paper 2020